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口腔修复与心理健康:修复程序更新对抑郁评分的影响。

Oral Rehabilitation and Mental Health: Effects of the Renew Procedure on Depression Scores.

作者信息

Cross Austin F, Balanoff William L, Schayes Bernard, Jayne William

机构信息

Research and Development, Renew LLC, Centennial, USA.

Medical Affairs, Emblem Health, New York, USA.

出版信息

Cureus. 2025 Jun 12;17(6):e85843. doi: 10.7759/cureus.85843. eCollection 2025 Jun.

DOI:10.7759/cureus.85843
PMID:40656387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12256034/
Abstract

The Renew Procedure is an elective comprehensive surgical and prosthetic intervention designed to address severe oral health issues, particularly periodontitis, and by systematically eliminating sources of chronic inflammation in the mouth, overall systemic health may improve. Additionally, restoring functionality and aesthetics to the mouth can significantly enhance a patient's quality of life. This study investigates whether improvements in oral health via the Renew Procedure correlate with measurable reductions in depressive symptoms, as assessed using the Patient Health Questionnaire-9 (PHQ-9), a pre- and post-operative assessment administered to patients undergoing full-mouth rehabilitation with the Renew Procedure. The results indicate a statistically significant decrease in PHQ-9 scores, suggesting that the intervention may contribute to improved mental health outcomes. These findings support the need for integrated healthcare approaches that recognize the interconnections between oral health, systemic inflammation, and mental well-being.

摘要

修复程序是一种选择性的综合外科和修复干预措施,旨在解决严重的口腔健康问题,特别是牙周炎,通过系统地消除口腔中的慢性炎症源,整体全身健康状况可能会得到改善。此外,恢复口腔的功能和美观可以显著提高患者的生活质量。本研究调查了通过修复程序改善口腔健康是否与使用患者健康问卷-9(PHQ-9)评估的抑郁症状的可测量减少相关,PHQ-9是对接受修复程序全口康复的患者进行术前和术后评估。结果表明,PHQ-9评分在统计学上有显著下降,表明该干预措施可能有助于改善心理健康结果。这些发现支持了综合医疗保健方法的必要性,这种方法认识到口腔健康、全身炎症和心理健康之间的相互联系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a8/12256034/0bc71d7061e2/cureus-0017-00000085843-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a8/12256034/0bc71d7061e2/cureus-0017-00000085843-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6a8/12256034/0bc71d7061e2/cureus-0017-00000085843-i01.jpg

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本文引用的文献

1
The Mediating Role of Formal Social Engagement in the Relationship Between Oral Health and Depressive Symptoms Among Older Adults in South Korea.正式社交参与在韩国老年人口腔健康与抑郁症状关系中的中介作用
Int J Geriatr Psychiatry. 2025 May;40(5):e70085. doi: 10.1002/gps.70085.
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Correlation between systemic immune-inflammatory index and graded diagnosis of periodontitis: a combined cross-sectional and retrospective study.全身免疫炎症指数与牙周炎分级诊断之间的相关性:一项横断面研究与回顾性研究相结合的研究
BMC Oral Health. 2024 Dec 23;24(1):1545. doi: 10.1186/s12903-024-05335-x.
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Social determinants of health linked with oral health in a representative sample of U.S. adults.
在美国成年人代表性样本中与口腔健康相关的健康社会决定因素。
BMC Oral Health. 2024 Dec 20;24(1):1518. doi: 10.1186/s12903-024-05257-8.
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Association study of depressive symptoms and periodontitis in an obese population: Analysis based on NHANES data from 2009 to 2014.肥胖人群中抑郁症状与牙周炎的关联研究:基于2009年至2014年美国国家健康与营养检查调查(NHANES)数据的分析
PLoS One. 2024 Dec 19;19(12):e0315754. doi: 10.1371/journal.pone.0315754. eCollection 2024.
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Mental Health, Socioeconomic Position, and Oral Health: A Path Analysis.心理健康、社会经济地位与口腔健康:路径分析。
Prev Chronic Dis. 2024 Oct 3;21:E76. doi: 10.5888/pcd21.240097.
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Independent and combined effects of smoking, drinking and depression on periodontal disease.吸烟、饮酒和抑郁对牙周病的独立和联合作用。
BMC Oral Health. 2024 May 6;24(1):535. doi: 10.1186/s12903-024-04287-6.
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Reducing Hemoglobin A1C Levels in Type II Diabetes: A Retrospective Analysis of the Renew Procedure.降低2型糖尿病患者的糖化血红蛋白水平:Renew程序的回顾性分析
Cureus. 2023 Oct 31;15(10):e48039. doi: 10.7759/cureus.48039. eCollection 2023 Oct.
8
Association between periodontitis and depression severity - A cross-sectional study of the older population in Hamburg.牙周炎与抑郁严重程度之间的关联——一项对汉堡老年人群的横断面研究。
Brain Behav Immun Health. 2023 Sep 25;34:100689. doi: 10.1016/j.bbih.2023.100689. eCollection 2023 Dec.
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Association between number of remaining teeth and incident depression in a rural Chilean cohort.剩余牙齿数量与智利农村队列人群中抑郁事件的相关性研究。
BMC Oral Health. 2023 Sep 4;23(1):633. doi: 10.1186/s12903-023-03374-4.
10
Mental Health and Oral Health in a Nationally Representative Cohort.全国代表性队列中的心理健康和口腔健康。
J Dent Res. 2023 Aug;102(9):1007-1014. doi: 10.1177/00220345231171108. Epub 2023 May 29.