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唐氏综合征患者胸骨切开术后的医源性胸壁畸形

Iatrogenic Pectus Deformities after Sternotomy in Patients with Down Syndrome.

作者信息

Haje Davi de Podestá, Aires Jorge Henrique Carlos, Sousa Talita Virginia Pinto de, Aquino Fernando Aurélio de Sá

机构信息

Centro Clínico Orthopectus, Brasília, DF, Brazil.

Department of Orthopedic Surgery, Hospital de Base do Distrito Federal, Brasília, DF, Brazil.

出版信息

Rev Bras Ortop (Sao Paulo). 2025 Jul 10;60(2):1-9. doi: 10.1055/s-0045-1809415. eCollection 2025 Apr.

DOI:10.1055/s-0045-1809415
PMID:40656675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12245552/
Abstract

OBJECTIVE

To evaluate the incidence of pectus deformity after sternotomy in patients with Down syndrome, in addition to the clinical and radiographic characteristics.

METHODS

There were 20 patients with sternotomy history during childhood and a control group (  = 20). The chest was clinically evaluated for the presence and type of pectus deformity, severity, and the clinical sternal body length. Radiographic examinations were used to evaluate any abnormalities.

RESULTS

From the total, 85% (  = 17) presented with pectus deformities (41% lateral pectus carinatum, 65% mild severity, and 29% little flexibility). In the control group, deformity occurred in 5% (  = 1). In the sternotomy group, 40% (  = 8) had a clinically shortened sternum, which did not occur in the control group (  = 0.01). Radiographic examination of the sternotomy with pectus group showed posterior angulations in the manubrium (10%), sternal shortening (38%), and irregularities in the sternal body (70%); furthermore, 36% of the children had all sternal growth plates closed, and 10% had early sterno-manubrial fusion, which did not occur in the control group.

CONCLUSION

Patients presented a high incidence of pectus deformity after sternotomy (mostly mild and of the lateral carinatum type), with radiographic changes suggestive of abnormal sternal growth.

摘要

目的

评估唐氏综合征患者胸骨切开术后鸡胸畸形的发生率,以及其临床和影像学特征。

方法

选取20例有儿童期胸骨切开术病史的患者和一个对照组(n = 20)。对胸部进行临床评估,以确定鸡胸畸形的存在、类型、严重程度以及临床胸骨体长。采用影像学检查评估有无异常。

结果

总体上,85%(n = 17)出现鸡胸畸形(41%为外侧鸡胸,65%为轻度严重程度,29%柔韧性差)。对照组中,畸形发生率为5%(n = 1)。在胸骨切开术组中,40%(n = 8)临床检查发现胸骨缩短,而对照组未出现(P = 0.01)。对有鸡胸畸形的胸骨切开术组进行影像学检查显示,胸骨柄后凸(10%)、胸骨缩短(38%)以及胸骨体不规则(70%);此外,36%的儿童所有胸骨生长板闭合,10%出现胸骨柄早期融合,对照组未出现这些情况。

结论

胸骨切开术后患者鸡胸畸形发生率较高(大多为轻度且为外侧鸡胸类型),影像学改变提示胸骨生长异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/00b7b2a6f4ec/10-1055-s-0045-1809415-i2400308en-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/b3dda8414f49/10-1055-s-0045-1809415-i2400308en-1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/e95aeceba5d9/10-1055-s-0045-1809415-i2400308en-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/0b896e97c6f5/10-1055-s-0045-1809415-i2400308en-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/00b7b2a6f4ec/10-1055-s-0045-1809415-i2400308en-6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/b3dda8414f49/10-1055-s-0045-1809415-i2400308en-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/43ecbaee8a05/10-1055-s-0045-1809415-i2400308en-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/19086bab5cc1/10-1055-s-0045-1809415-i2400308en-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/e95aeceba5d9/10-1055-s-0045-1809415-i2400308en-4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/0b896e97c6f5/10-1055-s-0045-1809415-i2400308en-5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8d7/12245552/00b7b2a6f4ec/10-1055-s-0045-1809415-i2400308en-6.jpg

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