Ali Fajar, Malak Anousheh, Wazir Safia, Fakhar Alishba, Jawad Malghalara
Saidu Medical College, Mingora Swat, Pakistan.
Obes Surg. 2025 Jul 14. doi: 10.1007/s11695-025-08071-5.
This Letter to the Editor evaluates Jense et al.'s (2025) study on MiniMizer ring-augmented Roux-en-Y gastric bypass (RYGB) for patients with BMI > 50 kg/m. While the study demonstrates promising outcomes-35.2% total weight loss (TWL) at 2 years and 83.3% diabetes remission-several limitations warrant discussion. Key concerns include (1) the absence of stratified data on ring diameters (6.5-8.0 cm), which obscures optimal size selection for balancing efficacy and complication risks; (2) limited applicability to revisional surgery, a common need for super-obese patients; and (3) insufficient reporting of micronutrient deficiencies and quality-of-life impacts, critical for holistic patient care. Additionally, the lack of cost-effectiveness analysis leaves the MiniMizer ring's economic justification unclear. We commend the authors' rigorous methodology but propose future research to address these gaps through standardized ring sizing, inclusion of revisional cases, and comprehensive nutritional and economic evaluations. These refinements would enhance the evidence base for ring-augmented RYGB in high-risk populations.
这封致编辑的信评估了延斯等人(2025年)关于MiniMizer环增强型Roux-en-Y胃旁路术(RYGB)用于体重指数(BMI)>50kg/m²患者的研究。虽然该研究显示出了有前景的结果——2年时总体重减轻(TWL)达35.2%,糖尿病缓解率达83.3%,但仍有几个局限性值得探讨。主要问题包括:(1)缺乏关于环直径(6.5 - 8.0厘米)的分层数据,这使得在平衡疗效和并发症风险时难以选择最佳尺寸;(2)对翻修手术的适用性有限,而这是超级肥胖患者常见需求;(3)对微量营养素缺乏和生活质量影响的报告不足,而这对全面的患者护理至关重要。此外,缺乏成本效益分析使得MiniMizer环的经济合理性尚不明确。我们赞扬作者严谨的方法,但建议未来的研究通过标准化环尺寸、纳入翻修病例以及进行全面的营养和经济评估来填补这些空白。这些改进将加强环增强型RYGB在高危人群中的证据基础。