Jansen Sem A M, Backes Manouk, Buck Dominique B, Nusmeier Anneliese, Timmermans Lucas, van Zutphen Stefan W A M, Edwards Michael J R, Hermans Erik, Nelen Stijn D
Department of Trauma Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
Department of Pediatric Surgery, Radboud University Medical Center, Nijmegen, the Netherlands.
Eur J Trauma Emerg Surg. 2025 Jul 14;51(1):253. doi: 10.1007/s00068-025-02916-5.
Pediatric trauma centers (PTCs) have been associated with lower mortality rates and increased use of non-operative management. While not formally designated, six trauma centers in the Netherlands meet PTC criteria and are referred to as designated pediatric trauma centers (dPTCs). This study aimed to evaluate the impact of treatment at dPTCs versus adult trauma centers (ATCs) on outcomes in severely injured pediatric patients in the Netherlands.
Data were obtained from the Dutch National Trauma Registry for patients aged ≤ 16 years with an Injury Severity Score (ISS) ≥ 16, admitted between January 1, 2015, and December 31, 2022. Multivariable logistic regression was performed to assess the impact of treatment at a dPTC on in-hospital mortality and Glasgow Outcome Scale (GOS) scores.
In total, 2,378 patients were included: 63% were treated in dPTCs, 17% in ATC-I, and 20% in ATC-II/III. Mortality rates were 13.1% in dPTCs, 12.6% in ATC-I, and 2.1% in ATC-II/III (p < 0.001). For children under 12 years of age, treatment at a dPTC was independently associated with a lower risk of in-hospital mortality compared to ATC-I (odds ratio [OR] 1.99, p = 0.017). dPTC treatment was also associated with more favorable GOS outcomes compared to ATC-I (OR 0.68, p = 0.022) and ATC-II/III (OR 0.34, p < 0.001).
Treatment at dPTCs is associated with a reduced risk of mortality for patients under 12 years of age and improved functional neurological outcomes. These findings support the further centralization of pediatric trauma care in the Netherlands.
儿科创伤中心(PTCs)与较低的死亡率以及非手术治疗的更多使用相关。荷兰有六个创伤中心虽未正式指定,但符合PTC标准,被称为指定儿科创伤中心(dPTCs)。本研究旨在评估在dPTCs与成人创伤中心(ATCs)接受治疗对荷兰严重受伤儿科患者结局的影响。
从荷兰国家创伤登记处获取2015年1月1日至2022年12月31日期间年龄≤16岁、损伤严重程度评分(ISS)≥16的患者数据。进行多变量逻辑回归以评估在dPTC接受治疗对院内死亡率和格拉斯哥预后量表(GOS)评分的影响。
总共纳入2378例患者:63%在dPTCs接受治疗,17%在ATC-I接受治疗,20%在ATC-II/III接受治疗。dPTCs的死亡率为13.1%,ATC-I为12.6%,ATC-II/III为2.1%(p<0.001)。对于12岁以下儿童,与ATC-I相比,在dPTC接受治疗与较低的院内死亡风险独立相关(比值比[OR]1.99,p=0.017)。与ATC-I(OR 0.68,p=0.022)和ATC-II/III(OR 0.34,p<0.001)相比,dPTC治疗也与更有利的GOS结局相关。
dPTCs治疗与12岁以下患者死亡率降低及神经功能结局改善相关。这些发现支持荷兰儿科创伤护理的进一步集中化。