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Encapsulation of the lipidated TLR7/8 agonist INI-4001 into ionic liposomes impacts H7 influenza antigen-specific immune responses.

作者信息

Mehradnia Fatemeh, Amin Hardik, Ferrini Maria E, Partlow Haley, Borgogna Timothy, Dachavaram Soma Shekar, T Ryter Kendal, Bazin Hélène G, Evans Jay T, Burkhart David J, DeBuysscher Blair, Abdelwahab Walid M

机构信息

Center for Translational Medicine-Adjuvant Research Team (CTM-ART), Missoula, MT, 59812, USA.

Department of Biomedical and Pharmaceutical Sciences, University of Montana, 32 Campus Drive, Missoula, MT, 59802, USA.

出版信息

Drug Deliv Transl Res. 2025 Jul 14. doi: 10.1007/s13346-025-01917-6.

DOI:10.1007/s13346-025-01917-6
PMID:40660065
Abstract
摘要

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本文引用的文献

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ProLonged Liposomal Delivery of TLR7/8 Agonist for Enhanced Cancer Vaccine.用于增强癌症疫苗的TLR7/8激动剂的长效脂质体递送
Vaccines (Basel). 2023 Sep 19;11(9):1503. doi: 10.3390/vaccines11091503.
2
A Comparison of Cellular Uptake Mechanisms, Delivery Efficacy, and Intracellular Fate between Liposomes and Extracellular Vesicles.脂质体和细胞外囊泡的细胞摄取机制、递送效率和细胞内命运比较。
Adv Healthc Mater. 2023 Oct;12(25):e2300319. doi: 10.1002/adhm.202300319. Epub 2023 Jul 9.
3
Host Recovery from Respiratory Viral Infection.宿主从呼吸道病毒感染中恢复。
Annu Rev Immunol. 2023 Apr 26;41:277-300. doi: 10.1146/annurev-immunol-101921-040450. Epub 2023 Jan 30.
4
Towards the development of subunit vaccines against tuberculosis: The key role of adjuvant.朝着结核亚单位疫苗的开发:佐剂的关键作用。
Tuberculosis (Edinb). 2023 Mar;139:102307. doi: 10.1016/j.tube.2023.102307. Epub 2023 Jan 14.
5
Recent advancement, immune responses, and mechanism of action of various vaccines against intracellular bacterial infections.针对细胞内细菌感染的各类疫苗的最新进展、免疫反应及作用机制。
Life Sci. 2023 Feb 1;314:121332. doi: 10.1016/j.lfs.2022.121332. Epub 2022 Dec 28.
6
Exploring the impact of physicochemical properties of liposomal formulations on their in vivo fate.探索脂质体制剂的物理化学性质对其体内命运的影响。
Life Sci. 2022 Jul 1;300:120574. doi: 10.1016/j.lfs.2022.120574. Epub 2022 Apr 23.
7
Current view on novel vaccine technologies to combat human infectious diseases.当前对抗人类传染病新型疫苗技术的看法。
Appl Microbiol Biotechnol. 2022 Jan;106(1):25-56. doi: 10.1007/s00253-021-11713-0. Epub 2021 Dec 10.
8
Exploration of Pattern Recognition Receptor Agonists as Candidate Adjuvants.探索模式识别受体激动剂作为候选佐剂。
Front Cell Infect Microbiol. 2021 Oct 6;11:745016. doi: 10.3389/fcimb.2021.745016. eCollection 2021.
9
Overcoming scientific barriers in the transition from to non-animal batch testing of human and veterinary vaccines.克服从动物批次试验到人用和兽用疫苗的非动物批次试验转变中的科学障碍。
Expert Rev Vaccines. 2021 Oct;20(10):1221-1233. doi: 10.1080/14760584.2021.1977628. Epub 2021 Sep 22.
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Platforms for Production of Protein-Based Vaccines: From Classical to Next-Generation Strategies.基于蛋白质的疫苗生产平台:从经典到下一代策略。
Biomolecules. 2021 Jul 21;11(8):1072. doi: 10.3390/biom11081072.