• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

螺旋旋转照射系统中多叶准直器驱动精度的评估:治疗期间叶片开启时间的定量分析。

Evaluation of multileaf collimator driving accuracy in helical rotational irradiation system: Quantitative analysis of leaf open time during treatment.

作者信息

Honda Hirofumi, Sasaki Motoharu, Tominaga Masahide, Omoto Kenji, Kido Teruhito

机构信息

Department of Radiological Technology, Ehime University Hospital, Toon, Ehime, Japan.

Graduate School of Advanced Technology and Science, Tokushima University, Tokushima, Japan.

出版信息

J Appl Clin Med Phys. 2025 Jul;26(7):e70186. doi: 10.1002/acm2.70186.

DOI:10.1002/acm2.70186
PMID:40660897
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12260261/
Abstract

BACKGROUND

The Radixact treatment system is equipped with a delivery analysis feature. This feature enables dose reconstruction using the patient's treatment-planning computed tomography scans and allows verification of the multileaf collimator (MLC) performance before and during treatment. In the Radixact system, the opening time of the MLC leaves is determined based on the treatment plan.

PURPOSE

This study aimed to evaluate MLC driving accuracy by assessing the MLC leaf open time (LOT) during treatment.

METHODS

Using Delivery Analysis version 2.3, we compared the treatment plan LOT with the LOT measured during treatment to determine the average and one standard deviation (%) of the LOT attainment rate. The analysis included comparisons of treated sites across 39 cases: nine prostate, eight pelvic, seven head, six chest, five head and neck (H&N), and four stereotactic body radiation therapy (SBRT) treatment plans.

RESULTS

The average and one standard deviation (%) of the LOT attainment rate for all patients on treatment was 94.56 ± 2.37. The values of each site were as follows: prostate, 95.93 ± 0.68; pelvis, 93.37 ± 2.16; head, 95.05 ± 1.99; chest, 97.61 ± 0.78; H&N, 92.44 ± 1.32; and SBRT, 98.39 ± 0.57. The treatment plans with the lowest attainment rates for each site were as follows: prostate, 95.19 ± 0.39; pelvis, 90.59 ± 0.16; head, 92.20 ± 0.15; chest, 95.76 ± 0.04; H&N, 90.55 ± 0.30; and SBRT, 97.32 ± 0.07. The plans with the largest one standard deviation (%) per site were as follows: prostate, ± 0.97; pelvis, ± 0.26; head, ± 0.57; chest, ± 0.23; H&N, ± 0.30; and SBRT, ± 0.07.

CONCLUSIONS

We proposed a simple method for quantitatively analyzing the LOT of an MLC. The average LOT attainment rate and its standard deviation varied by treatment site. Since the standard deviation differed by plan, the LOT attainment rate during treatment should be carefully monitored.

摘要

背景

瑞迪克斯(Radixact)治疗系统配备了剂量分析功能。该功能可利用患者的治疗计划计算机断层扫描进行剂量重建,并能在治疗前和治疗期间验证多叶准直器(MLC)的性能。在瑞迪克斯系统中,MLC叶片的开启时间是根据治疗计划确定的。

目的

本研究旨在通过评估治疗期间MLC叶片开启时间(LOT)来评价MLC驱动精度。

方法

使用剂量分析2.3版本,我们将治疗计划中的LOT与治疗期间测量的LOT进行比较,以确定LOT达成率的平均值和一个标准差(%)。分析包括对39例患者不同治疗部位的比较:9例前列腺、8例盆腔、7例头部、6例胸部、5例头颈部(H&N)和4例立体定向体部放射治疗(SBRT)治疗计划。

结果

所有接受治疗患者的LOT达成率平均值和一个标准差(%)为94.56±2.37。各部位的值如下:前列腺,95.93±0.68;盆腔,93.37±2.16;头部,95.05±1.99;胸部,97.61±0.78;头颈部,92.44±1.32;SBRT,98.39±0.57。各部位达成率最低的治疗计划如下:前列腺,95.19±0.39;盆腔,90.59±0.16;头部,92.20±0.15;胸部,95.76±0.04;头颈部,90.55±0.30;SBRT,97.32±0.07。各部位一个标准差(%)最大的计划如下:前列腺,±0.97;盆腔,±0.26;头部,±0.57;胸部,±0.23;头颈部,±0.30;SBRT,±0.07。

结论

我们提出了一种定量分析MLC的LOT的简单方法。LOT达成率的平均值及其标准差因治疗部位而异。由于标准差因计划而异,治疗期间的LOT达成率应仔细监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/2fe3601a7d11/ACM2-26-e70186-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/e6ea0f7ea220/ACM2-26-e70186-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/ab0d5162f14a/ACM2-26-e70186-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/fb82e59f2128/ACM2-26-e70186-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/2fe3601a7d11/ACM2-26-e70186-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/e6ea0f7ea220/ACM2-26-e70186-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/ab0d5162f14a/ACM2-26-e70186-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/fb82e59f2128/ACM2-26-e70186-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1917/12260261/2fe3601a7d11/ACM2-26-e70186-g002.jpg

相似文献

1
Evaluation of multileaf collimator driving accuracy in helical rotational irradiation system: Quantitative analysis of leaf open time during treatment.螺旋旋转照射系统中多叶准直器驱动精度的评估:治疗期间叶片开启时间的定量分析。
J Appl Clin Med Phys. 2025 Jul;26(7):e70186. doi: 10.1002/acm2.70186.
2
Enhancing Delivery Efficiency on the Magnetic Resonance-Linac: A Comprehensive Evaluation of Prostate Stereotactic Body Radiation Therapy Using Volumetric Modulated Arc Therapy.提高磁共振直线加速器的递送效率:使用容积调强弧形治疗对前列腺立体定向体部放射治疗的综合评估。
Int J Radiat Oncol Biol Phys. 2025 Jul 15;122(4):976-985. doi: 10.1016/j.ijrobp.2024.10.028. Epub 2024 Oct 26.
3
Non-measured and DVH-based patient-specific QA framework for lung SBRT VMAT with machine learning integration.基于非测量和剂量体积直方图(DVH)的肺癌立体定向体部放疗容积调强弧形治疗(VMAT)患者特异性质量保证框架与机器学习集成
Med Phys. 2025 Jul;52(7):e17975. doi: 10.1002/mp.17975.
4
Implementations of modulation complexity scores and their correlations with treatment plan quality in stereotactic radiation therapy.立体定向放射治疗中调制复杂度评分的实现及其与治疗计划质量的相关性
Med Phys. 2025 Jul;52(7):e17961. doi: 10.1002/mp.17961.
5
Online Adaptive Five-Fraction Ablative Radiotherapy for Prostate Cancer Using a Conventional Linear Accelerator.使用传统直线加速器的前列腺癌在线自适应五分割消融放疗
Pract Radiat Oncol. 2025 Jul-Aug;15(4):e371-e381. doi: 10.1016/j.prro.2025.01.013. Epub 2025 Feb 12.
6
Bladder filling dynamics during online adaptive prostate stereotactic body radiotherapy: Rationale for using an empty bladder workflow for treatment.在线自适应前列腺立体定向体部放射治疗期间的膀胱充盈动力学:采用膀胱排空流程进行治疗的原理。
Radiother Oncol. 2025 Aug;209:110978. doi: 10.1016/j.radonc.2025.110978. Epub 2025 Jun 2.
7
Biological adaptive radiotherapy for short-time dose compensation in lung SBRT patients.用于肺癌立体定向体部放疗患者短时间剂量补偿的生物适应性放疗。
Med Phys. 2025 Apr 14. doi: 10.1002/mp.17820.
8
Evaluation of the accuracy of an enhanced MLC leaf model for Linac-based stereotactic radiosurgery.基于直线加速器的立体定向放射外科中增强型多叶准直器叶片模型准确性的评估。
J Appl Clin Med Phys. 2025 Jul;26(7):e70143. doi: 10.1002/acm2.70143.
9
Intensity-modulated moderately hypofractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-C): early toxicity results from a randomised, open-label, phase 3, non-inferiority trial.强度调制中度低分割放疗与立体定向体部放疗治疗前列腺癌(PACE-C):一项随机、开放标签、3期、非劣效性试验的早期毒性结果
Lancet Oncol. 2025 Jul;26(7):936-947. doi: 10.1016/S1470-2045(25)00205-0. Epub 2025 Jun 12.
10
Evaluation of the efficacy of automated machine learning enhanced planning system and a comparative analysis with manual planning system.自动化机器学习增强型计划系统的疗效评估及与手动计划系统的对比分析。
J Cancer Res Ther. 2025 Apr 1;21(3):593-601. doi: 10.4103/jcrt.jcrt_1373_24. Epub 2025 Jul 5.

本文引用的文献

1
Which failures do patient-specific quality assurance systems need to catch?针对特定患者的质量保证系统需要发现哪些故障?
Med Phys. 2025 Jan;52(1):88-98. doi: 10.1002/mp.17468. Epub 2024 Oct 28.
2
Performance of binary MLC using real-time optical sensor feedback system.使用实时光学传感器反馈系统的二进制 MLC 性能。
J Appl Clin Med Phys. 2024 Nov;25(11):e14506. doi: 10.1002/acm2.14506. Epub 2024 Sep 9.
3
Validation of MLC leaf open time calculation methods for PSQA in adaptive radiotherapy with tomotherapy units.利用螺旋断层放疗设备对自适应放疗的 PSQA 进行 MLC 叶片开放时间计算方法的验证。
J Appl Clin Med Phys. 2024 Oct;25(10):e14478. doi: 10.1002/acm2.14478. Epub 2024 Aug 8.
4
Evaluating AAPM-TG-218 recommendations: Gamma index tolerance and action limits in IMRT and VMAT quality assurance using SunCHECK.评估 AAPM-TG-218 建议:使用 SunCHECK 对 IMRT 和 VMAT 质量保证进行 Gamma 指数容限和行动限评估。
J Appl Clin Med Phys. 2024 Jun;25(6):e14277. doi: 10.1002/acm2.14277. Epub 2024 Jan 19.
5
Quantitative assessment of helical tomotherapy plans complexity.螺旋断层放疗计划复杂度的定量评估。
J Appl Clin Med Phys. 2023 Jan;24(1):e13781. doi: 10.1002/acm2.13781. Epub 2022 Dec 15.
6
AAPM Task Group Report 306: Quality control and assurance for tomotherapy: An update to Task Group Report 148.美国医学物理师协会任务组报告306:断层放射治疗的质量控制与保证:对任务组报告148的更新
Med Phys. 2023 Mar;50(3):e25-e52. doi: 10.1002/mp.16150. Epub 2023 Jan 23.
7
Usability of detecting delivery errors during treatment of prostate VMAT with a gantry-mounted transmission detector.使用带有龙门架传输探测器检测前列腺 VMAT 治疗中传输误差的可用性。
J Appl Clin Med Phys. 2021 Jul;22(7):66-76. doi: 10.1002/acm2.13260. Epub 2021 May 5.
8
Leaf open time sinogram (LOTS): a novel approach for patient specific quality assurance of total marrow irradiation.叶开放时间闪烁摄影术(LOTS):一种用于总骨髓照射患者特异性质量保证的新方法。
Radiat Oncol. 2020 Oct 14;15(1):236. doi: 10.1186/s13014-020-01669-2.
9
A delivery quality assurance tool based on the actual leaf open times in tomotherapy.一种基于螺旋断层放射治疗中实际叶片开启时间的交付质量保证工具。
Med Phys. 2020 Sep;47(9):3845-3851. doi: 10.1002/mp.14348. Epub 2020 Jul 18.
10
Estimating dose delivery accuracy in stereotactic body radiation therapy: A review of in-vivo measurement methods.立体定向体部放射治疗中剂量传递精度的评估:体内测量方法的综述。
Radiother Oncol. 2020 Aug;149:158-167. doi: 10.1016/j.radonc.2020.05.014. Epub 2020 May 19.