Suppr超能文献

使用实时光学传感器反馈系统的二进制 MLC 性能。

Performance of binary MLC using real-time optical sensor feedback system.

机构信息

Radiotherapy Center, Gruppo Ospedaliero Moncucco, Clinica Moncucco, Lugano, Switzerland.

出版信息

J Appl Clin Med Phys. 2024 Nov;25(11):e14506. doi: 10.1002/acm2.14506. Epub 2024 Sep 9.

Abstract

The Radixact system (Accuray Inc., Sunnyvale, CA) is the latest platform release based on the TomoTherapy technology. The most recent system does not apply a leaf latency model correction after plan optimization to ensure the correct MLC leaf-open time (LOT) agreement between the TPS and machine delivery. The MLC uses optical sensors to measure the delivered LOTs in real-time and individual leaf-specific latency corrections are made to ensure agreement. The aim of this study was to assess the performance of the Radixact MLC with leaf-specific latency correction using the optical sensor's real-time feedback. Specifically, the study statistically evaluated the MLC LOT errors observed from 290 plan-specific quality assurance (PSQA) measurements. Repeatability testing was performed to quantify the uncertainty in the MLC feedback system delivery by analyzing > 1300 delivered treatment fractions throughout the course of radiotherapy. The clinical impact was evaluated by estimating the resulting dose difference in the patient targets due to the measured plan latencies. Our study measured an average plan latency equal to 2.0 ± 0.4 ms (0.6% ± 0.2%) for 290 PSQAs. Repeatability tests showed a mean standard deviation in plan latencies measuring 0.05 ms (0.02%). The deviation from the TPS in the mean target dose due to the plan latencies was estimated to be 0.0% ± 0.2% (range: -0.7%-1.1%). The current MLC system with real-time optical sensor feedback is capable of accurately delivering the TPS-generated sinograms. Repeatability test results showed that the system allows for high reliability in daily sinogram delivery. The MLC latency deviations were shown to have minimal clinical impact on the overall target dosimetry.

摘要

Radixact 系统(Accuray Inc.,加利福尼亚州森尼韦尔)是基于 TomoTherapy 技术的最新平台版本。最新系统在计划优化后不应用叶延迟模型校正,以确保 TPS 和机器交付之间的正确 MLC 叶开启时间 (LOT) 协议。MLC 使用光学传感器实时测量交付的 LOT,并进行个别叶片特定的延迟校正,以确保协议。本研究的目的是使用光学传感器的实时反馈评估带有叶片特定延迟校正的 Radixact MLC 的性能。具体来说,该研究从 290 个特定于计划的质量保证 (PSQA) 测量中统计评估了 MLC LOT 误差。通过分析整个放射治疗过程中超过 1300 个交付的治疗分数,进行重复性测试以量化 MLC 反馈系统交付的不确定性。通过估计由于测量的计划延迟而导致患者靶区的剂量差异来评估临床影响。我们的研究测量了 290 个 PSQA 的平均计划延迟为 2.0 ± 0.4 ms(0.6% ± 0.2%)。重复性测试显示,计划延迟的平均标准偏差为 0.05 ms(0.02%)。由于计划延迟,目标剂量的 TPS 偏差估计为 0.0% ± 0.2%(范围:-0.7%-1.1%)。具有实时光学传感器反馈的当前 MLC 系统能够准确地交付 TPS 生成的正弦图。重复性测试结果表明,该系统允许在日常正弦图交付中具有高度的可靠性。MLC 延迟偏差对总体靶区剂量学的临床影响最小。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e56d/11539967/d11721b80288/ACM2-25-e14506-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验