Jequier E, Schutz Y
Int J Obes. 1985;9 Suppl 2:1-7.
A reduced thermogenic response to food ingestion may contribute to the dynamic phase of weight gain in obesity. A defect in diet-induced thermogenesis has been reported in about one third of an unselected group of obese women. After inducing weight loss with a hypocaloric diet, the thermogenic defect does not disappear. Since basal metabolic rate decreases with weight loss, the overall postprandial energy expenditure of 'post-obese' individuals can be lower than that of lean controls. As a consequence, post-obese subjects must reset energy intake to a lower level than the previous maintenance food consumption in order to avoid relapse of body weight gain.
对食物摄入的产热反应降低可能导致肥胖症体重增加的动态阶段。在一组未经挑选的肥胖女性中，约三分之一的人被报道存在饮食诱导产热缺陷。在采用低热量饮食诱导体重减轻后，产热缺陷并未消失。由于基础代谢率会随着体重减轻而降低，“肥胖后”个体的总体餐后能量消耗可能低于瘦对照组。因此，肥胖后个体必须将能量摄入重置为低于先前维持食物摄入量的水平，以避免体重再次增加。
