Storey E, Feik S A
J Anat. 1985 Jan;140 ( Pt 1)(Pt 1):37-48.
Sprague-Dawley rats weighing 50 g were divided into two groups: (i) control, (ii) rats with tails bent in situ incorporating 7, 5 and 3 caudal vertebrae in the loop. Tails were radiographed weekly up to six weeks and a microradiographic and histological study undertaken on selected specimens. Results showed that the bones in the apex of the loop of the bent tail moved through their investing soft tissues towards the outer side of the bend, the joints became V-shaped and in tails bent acutely the epiphyses and metaphyses tilted. By six weeks the bones appeared bent with a thinner straight to convex shaft on the outer side and a thicker, more concave one on the inner side. The changes observed can be explained by taking into account (i) strain within the bone, (ii) altered growth and (iii) the translation of bones through their investing soft tissues. The results are consistent with the supposition that, on application of a continuous moderate stress, tension induces formation and pressure resorption of bone.
将50克重的Sprague-Dawley大鼠分为两组：（i）对照组，（ii）尾巴原位弯曲组，弯曲环内包含7、5和3节尾椎骨。每周对尾巴进行X线摄影，持续六周，并对选定的标本进行显微放射摄影和组织学研究。结果表明，弯曲尾巴环顶端的骨头穿过其周围的软组织向弯曲外侧移动，关节呈V形，在急性弯曲的尾巴中，骨骺和干骺端倾斜。到六周时，骨头看起来弯曲，外侧的骨干较薄，从直变凸，内侧较厚且更凹陷。观察到的这些变化可以通过考虑以下因素来解释：（i）骨内应变，（ii）生长改变，（iii）骨头穿过其周围软组织的移位。这些结果与以下假设一致，即在持续施加适度应力时，张力诱导骨的形成和压力吸收。
