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阿联酋7至10岁儿童的龋齿与PROP基因味觉易感性

Dental caries and PROP genetic taste predisposition in UAE 7-10 years old.

作者信息

Walia T, Al Shami R, Berdouses Ε D, Shetty R M, Kaklamanos E G, Kavvadia K, Hashim R, Baroudi K

机构信息

Department of Clinical Sciences, College of Dentistry, Ajman University, Ajman, United Arab Emirates.

Datta Meghe Institute of Higher Education and Research (Declared as Deemed-to-be University), Wardha, India.

出版信息

Eur Arch Paediatr Dent. 2025 Jul 15. doi: 10.1007/s40368-025-01080-z.

DOI:10.1007/s40368-025-01080-z
PMID:40665086
Abstract

PURPOSE

The present study aimed to assess the prevalence of tasters and non-tasters among children using a 6-n-propylthiouracil (PROP) taste test, and to investigate the association between taste predisposition, caries experience severity, oral hygiene practices, and dietary habits.

METHODS

200 children aged 7-10 years underwent a PROP filter paper taste test. Dental caries experience was assessed using the ICDAS system, and data on oral hygiene and dietary habits were collected via a questionnaire. A training form was implemented to ensure comprehension of the general labelled magnitude (gLMS) scale. Scores on this scale were used to categorise individuals into super-tasters, medium tasters, and non-tasters.

RESULTS

Super-tasters were the most prevalent genetic taste sensitivity phenotype (54.0%), followed by non-tasters (23.5%) and medium tasters (22.5%). Non-tasters demonstrated higher caries experience and severity, compared to tasters (p < 0.001). Non-tasters were three times more likely to snack frequently and had lower brushing frequency. Tasters reported fewer snacking occurrences.

CONCLUSION

Non-tasters, identified by the PROP sensitivity test, had higher caries experience, more frequent snacking and soft drink consumption and less frequent brushing.

摘要

目的

本研究旨在通过6-正丙基硫氧嘧啶(PROP)味觉测试评估儿童中味觉敏感者和味觉不敏感者的患病率,并调查味觉易感性、龋齿经历严重程度、口腔卫生习惯和饮食习惯之间的关联。

方法

200名7至10岁的儿童接受了PROP滤纸味觉测试。使用国际龋病检测与评估系统(ICDAS)评估龋齿经历,并通过问卷收集口腔卫生和饮食习惯的数据。实施了一份培训表格以确保对通用标记量值(gLMS)量表的理解。该量表上的分数用于将个体分为超味觉者、中等味觉者和味觉不敏感者。

结果

超味觉者是最常见的遗传味觉敏感表型(54.0%),其次是味觉不敏感者(23.5%)和中等味觉者(22.5%)。与味觉敏感者相比,味觉不敏感者表现出更高的龋齿经历和严重程度(p < 0.001)。味觉不敏感者频繁吃零食的可能性是味觉敏感者的三倍,刷牙频率更低。味觉敏感者报告的吃零食次数较少。

结论

通过PROP敏感性测试确定的味觉不敏感者有更高的龋齿经历、更频繁的吃零食和饮用软饮料以及更低的刷牙频率。

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本文引用的文献

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The Number of Fungiform Papillae, Taste Sensitivity and Smell Functions of Children Aged 11-15.11-15 岁儿童的菌状乳头数量、味觉敏感性和嗅觉功能。
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Genetic taste sensitivity and dental caries in children and adolescents: A systematic review and meta-analysis.遗传味觉敏感性与儿童和青少年龋齿:系统评价和荟萃分析。
Int J Paediatr Dent. 2022 Mar;32(2):204-222. doi: 10.1111/ipd.12845. Epub 2021 Jul 9.
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Determinants of dental caries in children in the Middle East and North Africa region: a systematic review based on literature published from 2000 to 2019.
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Longitudinal Associations Between Taste Sensitivity, Taste Liking, Dietary Intake and BMI in Adolescents.青少年味觉敏感性、味觉偏好、饮食摄入与体重指数之间的纵向关联
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Caries Res. 2011;45(6):556-60. doi: 10.1159/000332432. Epub 2011 Oct 28.
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