• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Remifentanil Attenuates LPS-Induced Genital Tract Injury by Modulating Inflammation, Oxidative Stress, and Mitochondrial Gene Expression in a Rat Sepsis Model.

作者信息

Ozmen Ozlem, Asci Halil, Topsakal Senay, Taner Rumeysa, Oktem Mert, Ozcan Kadriye Nilay, Aydin Bunyamin

机构信息

Department of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur, Türkiye.

Department of Pharmacology, Faculty of Medicine, Suleyman Demirel University, Isparta, Türkiye.

出版信息

Reprod Sci. 2025 Jul 15. doi: 10.1007/s43032-025-01930-7.

DOI:10.1007/s43032-025-01930-7
PMID:40665109
Abstract
摘要

相似文献

1
Remifentanil Attenuates LPS-Induced Genital Tract Injury by Modulating Inflammation, Oxidative Stress, and Mitochondrial Gene Expression in a Rat Sepsis Model.瑞芬太尼通过调节大鼠脓毒症模型中的炎症、氧化应激和线粒体基因表达减轻脂多糖诱导的生殖道损伤。
Reprod Sci. 2025 Jul 15. doi: 10.1007/s43032-025-01930-7.
2
Ebselen Alleviates Sepsis-Induced Acute Kidney Injury by Regulating Endoplasmic Reticulum Stress, Apoptosis, and Oxidative Stress.依布硒啉通过调节内质网应激、细胞凋亡和氧化应激减轻脓毒症诱导的急性肾损伤。
Vet Med Sci. 2025 Mar;11(2):e70318. doi: 10.1002/vms3.70318.
3
LL-37 Attenuates Sepsis-Induced Lung Injury by Alleviating Inflammatory Response and Epithelial Cell Oxidative Injury via ZBP1-Mediated Autophagy.LL-37通过ZBP1介导的自噬减轻炎症反应和上皮细胞氧化损伤，从而减轻脓毒症诱导的肺损伤。
Toxins (Basel). 2025 Jun 17;17(6):306. doi: 10.3390/toxins17060306.
4
4-Octyl itaconate alleviates endothelial cell inflammation and barrier dysfunction in LPS-induced sepsis via modulating TLR4/MAPK/NF-κB signaling : 4-Octyl itaconate alleviates endothelial dysfunction.衣康酸辛酯通过调节TLR4/MAPK/NF-κB信号通路减轻脂多糖诱导的脓毒症中的内皮细胞炎症和屏障功能障碍：衣康酸辛酯减轻内皮功能障碍。
Mol Med. 2025 Jun 16;31(1):240. doi: 10.1186/s10020-025-01160-2.
5
Taurine alleviates oxidative stress, inflammation, and mitochondrial apoptosis in lipopolysaccharide-induced bovine endometrial epithelial cells by activating nrf2/HO-1 and inhibiting TLR4-mapk/NF-κb and Caspase-3 pathways.牛磺酸通过激活Nrf2/HO-1并抑制TLR4-MAPK/NF-κB和半胱天冬酶-3途径，减轻脂多糖诱导的牛子宫内膜上皮细胞中的氧化应激、炎症和线粒体凋亡。
Eur J Pharmacol. 2025 Sep 15;1003:177986. doi: 10.1016/j.ejphar.2025.177986. Epub 2025 Jul 22.
6
Effect of dapagliflozin on sepsis-induced kidney injury in a rat model: modulation of the NLRP3 pathway.达格列净对大鼠模型中脓毒症诱导的肾损伤的影响：NLRP3途径的调节
Immunopharmacol Immunotoxicol. 2025 Jun 18:1-8. doi: 10.1080/08923973.2025.2519597.
7
Fluvoxamine Attenuates Liver Injury in Lipopolysaccharide-Induced Sepsis: Via Nrf2/HO-1 Pathway.氟伏沙明减轻脂多糖诱导的脓毒症中的肝损伤：通过Nrf2/HO-1途径
Fundam Clin Pharmacol. 2025 Aug;39(4):e70031. doi: 10.1111/fcp.70031.
8
Micromeria congesta Alleviates LPS-Induced Inflammation, Apoptosis, Oxidative Stress and DNA Damage in Rat Heart and Kidneys.密花姜味草减轻脂多糖诱导的大鼠心脏和肾脏炎症、细胞凋亡、氧化应激及DNA损伤
Vet Med Sci. 2025 Mar;11(2):e70264. doi: 10.1002/vms3.70264.
9
Orexin-A Attenuates the Inflammatory Response in Sepsis-Associated Encephalopathy by Modulating Oxidative Stress and Inhibiting the ERK/NF-κB Signaling Pathway in Microglia and Astrocytes.食欲素-A 通过调节氧化应激和抑制小胶质细胞和星形胶质细胞中的 ERK/NF-κB 信号通路来减轻脓毒症相关性脑病的炎症反应。
CNS Neurosci Ther. 2024 Nov;30(11):e70096. doi: 10.1111/cns.70096.
10
Low-Dose Lipopolysaccharide Alleviates Neuronal Apoptosis and Oxidative Stress in Rats with Spinal Cord Injury by Inducing Nrf2 m6A Methylation Modification via Suppressing ALKBH5.低剂量脂多糖通过抑制ALKBH5诱导Nrf2 m6A甲基化修饰减轻脊髓损伤大鼠的神经元凋亡和氧化应激。
Neurochem Res. 2025 Jun 7;50(3):188. doi: 10.1007/s11064-025-04442-7.

本文引用的文献

1
Advances in the Regulation of Inflammatory Mediators in Nitric Oxide Synthase: Implications for Disease Modulation and Therapeutic Approaches.一氧化氮合酶中炎症介质调节的进展：对疾病调节和治疗方法的影响。
Int J Mol Sci. 2025 Jan 30;26(3):1204. doi: 10.3390/ijms26031204.
2
Investigating the protective effects of fluvoxamine against sepsis-related acute lung injury through antiapoptotic, anti-inflammatory, and anti-oxidant features in rats.通过抗凋亡、抗炎和抗氧化特性研究氟伏沙明对大鼠脓毒症相关急性肺损伤的保护作用。
Iran J Basic Med Sci. 2025;28(3):323-331. doi: 10.22038/ijbms.2024.80608.17444.
3
Remifentanil Ameliorates Lipopolysaccharide-Induced Neuroinflammation by Regulating the Phosphatidylinositol 3-Kinase/Serine-Threonine Protein Kinase/Hypoxia-Inducible Factor 1 Alpha Pathway.
瑞芬太尼通过调节磷脂酰肌醇3激酶/丝氨酸-苏氨酸蛋白激酶/缺氧诱导因子1α通路改善脂多糖诱导的神经炎症。
Pharmacol Res Perspect. 2025 Feb;13(1):e70071. doi: 10.1002/prp2.70071.
4
Fluvoxamine Inhibited NLRP3 and NF-κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD-MPR, KISS-1, AQP4 and Claudin-1 Expressions.氟伏沙明通过改善CD-MPR、KISS-1、水通道蛋白4（AQP4）和闭合蛋白-1（Claudin-1）的表达来抑制NLRP3和NF-κB炎症通路并维持生殖功能。
Basic Clin Pharmacol Toxicol. 2025 Mar;136(3):e70000. doi: 10.1111/bcpt.70000.
5
The NRF-2/HO-1 Signaling Pathway: A Promising Therapeutic Target for Metabolic Dysfunction-Associated Steatotic Liver Disease.NRF-2/HO-1信号通路：代谢功能障碍相关脂肪性肝病的一个有前景的治疗靶点。
J Inflamm Res. 2024 Nov 3;17:8061-8083. doi: 10.2147/JIR.S490418. eCollection 2024.
6
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia.受损的内皮细胞 Wnt/β-catenin 信号通路介导内毒素血症时血脑屏障的破坏，并导致神经炎症。
J Neuroinflammation. 2024 Oct 19;21(1):265. doi: 10.1186/s12974-024-03261-x.
7
Oxyresveratrol reduces lipopolysaccharide-induced inflammation and oxidative stress through inactivation of MAPK and NF-κB signaling in brain endothelial cells.氧化白藜芦醇通过使脑内皮细胞中的丝裂原活化蛋白激酶（MAPK）和核因子κB（NF-κB）信号失活来减轻脂多糖诱导的炎症和氧化应激。
Biochem Biophys Rep. 2024 Sep 7;40:101823. doi: 10.1016/j.bbrep.2024.101823. eCollection 2024 Dec.
8
Penehyclidine hydrochloride alleviates LPS-induced inflammatory responses and oxidative stress via ROS/Nrf2/HO-1 activation in RAW264.7 cells.盐酸戊乙奎醚通过激活RAW264.7细胞中的ROS/Nrf2/HO-1减轻脂多糖诱导的炎症反应和氧化应激。
Adv Clin Exp Med. 2025 Jan;34(1):101-111. doi: 10.17219/acem/183883.
9
NF-κB in biology and targeted therapy: new insights and translational implications.生物学与靶向治疗中的核因子-κB：新见解与转化意义
Signal Transduct Target Ther. 2024 Mar 4;9(1):53. doi: 10.1038/s41392-024-01757-9.
10
Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review.感染性疾病中的促炎和抗炎白细胞介素：综述
Trop Med Infect Dis. 2024 Jan 4;9(1):13. doi: 10.3390/tropicalmed9010013.