感染性疾病中的促炎和抗炎白细胞介素：综述
Pro-Inflammatory and Anti-Inflammatory Interleukins in Infectious Diseases: A Comprehensive Review.
作者信息
Al-Qahtani Arwa A, Alhamlan Fatimah S, Al-Qahtani Ahmed Ali
机构信息
Department of Family Medicine, College of Medicine, Al-Imam Mohammad Ibn Saud Islamic University, Riyadh 11432, Saudi Arabia.
Department of Infection and Immunity, King Faisal Specialist Hospital & Research Center, Riyadh 11211, Saudi Arabia.
出版信息
Trop Med Infect Dis. 2024 Jan 4;9(1):13. doi: 10.3390/tropicalmed9010013.
Interleukins (ILs) are signaling molecules that are crucial in regulating immune responses during infectious diseases. Pro-inflammatory ILs contribute to the activation and recruitment of immune cells, whereas anti-inflammatory ILs help to suppress excessive inflammation and promote tissue repair. Here, we provide a comprehensive overview of the role of pro-inflammatory and anti-inflammatory ILs in infectious diseases, with a focus on the mechanisms underlying their effects, their diagnostic and therapeutic potential, and emerging trends in IL-based therapies.
白细胞介素（ILs）是在传染病期间调节免疫反应中起关键作用的信号分子。促炎白细胞介素有助于免疫细胞的激活和募集，而抗炎白细胞介素则有助于抑制过度炎症并促进组织修复。在这里，我们全面概述了促炎和抗炎白细胞介素在传染病中的作用，重点关注其作用机制、诊断和治疗潜力以及基于白细胞介素的疗法的新趋势。
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