Suppr超能文献

使用3D打印髁支撑晶格金属植入物和腓骨移植重建大型股骨远端骨巨细胞瘤:一种新颖的生物力学和手术方法。

Reconstruction of a large distal femoral giant cell tumor using a 3D-printed condylar support lattice metal implant and fibular grafts: a novel biomechanical and surgical approach.

作者信息

Chaudhry Aashish, Sambharia Abhishek Kumar, Bahre Bharat, Pandey Mani, Chawla Tanvi

机构信息

Department of Orthopedics and Joint Replacement, Aakash Healthcare Superspeciality Hospital, New Delhi, India.

Department of Clinical Research, Aakash Healthcare Super speciality Hospital, New Delhi, India.

出版信息

3D Print Med. 2025 Jul 16;11(1):38. doi: 10.1186/s41205-025-00282-x.

Abstract

OBJECTIVE

This study presents a novel approach to reconstructing a large defect in the load-bearing condylar region of distal femur following the surgical removal of a giant cell tumor (GCT). By using advanced 3D printing technology and virtual surgical planning, designing a patient-specific implant (PSI) to replace the defect and integrate a fibular graft for osseointegration, providing cortical bone strength.

METHODS

A 40-year-old female patient with recurrent pain and swelling in the left knee was diagnosed with a distal femoral GCT. Imaging studies confirmed a large lytic lesion with cortical thinning. After tumor excision, reconstruction was performed using a 3D-printed lattice metal implant designed for biological and mechanical integration. A 3D printed custom titanium plate was used additionally for structural support and a fibular graft was embedded within the implant for biological union.

RESULTS

Postoperative outcomes demonstrated progressive osseointegration, weight-bearing capability, and functional recovery. The patient regained maximum osseointegration with the completion of 6 months and full-strength unrestricted mobility at the end of 18 months postoperatively without recurrence. Radiographic follow-ups confirmed structural integrity and graft incorporation.

CONCLUSION

This study illustrates the successful application of a customized lattice metal implant integrated with a fibular graft, demonstrating its feasibility for large tumor-induced defects in weight-bearing regions.

摘要

目的

本研究提出了一种新方法,用于在手术切除股骨远端巨大细胞瘤(GCT)后重建其负重髁区的大缺损。通过使用先进的3D打印技术和虚拟手术规划,设计定制的植入物(PSI)来替代缺损,并整合腓骨移植以实现骨整合,提供皮质骨强度。

方法

一名40岁女性患者,左膝反复疼痛和肿胀,被诊断为股骨远端GCT。影像学检查证实有一个大的溶骨性病变,伴有皮质变薄。肿瘤切除后,使用为生物和机械整合设计的3D打印点阵金属植入物进行重建。另外使用3D打印的定制钛板进行结构支撑,并将腓骨移植嵌入植入物内以实现生物结合。

结果

术后结果显示骨整合逐渐进行,具备负重能力和功能恢复。患者在术后6个月时实现了最大程度的骨整合,术后18个月结束时恢复了无限制的全强度活动,且无复发。影像学随访证实了结构完整性和移植骨融合情况。

结论

本研究说明了定制的点阵金属植入物与腓骨移植相结合的成功应用,证明了其在负重区域大肿瘤所致缺损中的可行性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c7c/12265116/c0e2d9a0f524/41205_2025_282_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验