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对阿尔茨海默病具有抗年龄衰退性(“保持性”)的韦氏成人智力量表(WAIS)子测验的敏感性。

Sensitivity of age-decline resistant ("hold") WAIS subtests to Alzheimer's disease.

作者信息

Larrabee G J, Largen J W, Levin H S

出版信息

J Clin Exp Neuropsychol. 1985 Oct;7(5):497-504. doi: 10.1080/01688638508401281.

DOI:10.1080/01688638508401281
PMID:4066906
Abstract

WAIS age-decline-resistant ("hold") and age-decline-sensitive ("don't hold") subtests were both effective in discriminating 25 patients with Alzheimer-type dementia (DAT) from 25 normal elderly subjects who were matched on age, education, and sex. We found that global ratings of severity of dementia correlated significantly with the WAIS Information and Digit Symbol subtests, but not with memory test scores. These data indicate that (1) the practice of estimating premorbid ability based on current "hold" test performance should be abandoned, and (2) the utility of memory tests is greatest for initial diagnosis of DAT, while WAIS cognitive variables may be more useful in evaluating DAT severity.

摘要

韦氏成人智力量表中对年龄衰退有抵抗力的(“保持”)和对年龄衰退敏感的(“不保持”)分测验,在区分25名阿尔茨海默型痴呆(DAT)患者与25名在年龄、教育程度和性别上相匹配的正常老年受试者时均有效。我们发现,痴呆严重程度的总体评分与韦氏成人智力量表的信息和数字符号分测验显著相关,但与记忆测验分数无关。这些数据表明:(1)基于当前“保持”测验表现来估计病前能力的做法应被摒弃;(2)记忆测验在DAT的初始诊断中效用最大,而韦氏成人智力量表的认知变量在评估DAT严重程度方面可能更有用。

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