Wang Zhongqing, Chen Keyi, Yang Shun
Department of Hand and Wrist Surgery, Sichuan Province Orthopaedic Hospital, Chengdu, 610000, Sichuan, China.
Eur J Pediatr. 2025 Jul 16;184(8):487. doi: 10.1007/s00431-025-06309-z.
Previous studies have shown that grip strength reflects not only muscle function but also relates to bone mineral density (BMD) in adults. However, its association with BMD in adolescents remains unclear. This study aimed to examine the correlation between grip strength and BMD among US adolescents aged 12-19 years.
Data were drawn from the National Health and Nutrition Examination Survey (NHANES) 2011-2014, including 1,752 adolescents aged 12-19 years. Combined grip strength was defined as the sum of the maximum readings from each hand using a hand-held dynamometer. BMD of the right leg, trunk, and whole body was measured using dual-energy X-ray absorptiometry (DXA). Univariate and multivariate linear regression models were applied to assess the relationship between grip strength and BMD.
After adjustment for age, ethnicity, body mass index (BMI), smoking status, alcohol consumption, calcium and vitamin D supplementation, and serum calcium and phosphorus levels, grip strength showed a positive association with right leg BMD [β = 0.004, 95% CI: (0.004, 0.004)], trunk BMD [β = 0.004, 95% CI: (0.004, 0.004)], and whole-body BMD [β = 0.003, 95% CI: (0.003, 0.004)] (p < 0.001).
(1) Grip strength was positively associated with right leg, trunk, and whole-body BMD among American adolescents aged 12-19 years. (2) Hand grip strength may serve as a useful indicator in assessing skeletal health in this age group.
• A significant positive association persists between handgrip strength and bone mineral density among adolescents.
• Literature is not avallable regarding sports participation and pubertal status with bone mineral density in adolescents.
既往研究表明，握力不仅反映肌肉功能，还与成年人的骨密度（BMD）有关。然而，其与青少年骨密度的关联仍不明确。本研究旨在探讨美国12 - 19岁青少年握力与骨密度之间的相关性。
数据来自2011 - 2014年国家健康与营养检查调查（NHANES），包括1752名12 - 19岁的青少年。联合握力定义为使用手持式测力计测量的每只手最大读数之和。使用双能X线吸收法（DXA）测量右腿、躯干和全身的骨密度。应用单变量和多变量线性回归模型评估握力与骨密度之间的关系。
在调整年龄、种族、体重指数（BMI）、吸烟状况、饮酒情况、钙和维生素D补充剂以及血清钙和磷水平后，握力与右腿骨密度[β = 0.004, 95%置信区间：(0.004, 0.004)]、躯干骨密度[β = 0.004, 95%置信区间：(0.004, 0.004)]和全身骨密度[β = 0.003, 95%置信区间：(0.003, 0.004)]呈正相关（p < 0.001）。
（1）12 - 19岁美国青少年的握力与右腿、躯干和全身骨密度呈正相关。（2）握力可能是评估该年龄组骨骼健康的有用指标。
•青少年握力与骨密度之间存在显著正相关。
•关于青少年运动参与和青春期状态与骨密度的文献尚不可得。
