Yang Fanjing, Gong Xiaojiao, Zhao Pan, Cheng Lingtong, Zhang Yujie, Luo Yingting, Zhu Qian-Hao, Ye Chu-Yu
Institute of Crop Science, Zhejiang Key Laboratory of Crop Germplasm Innovation and Utilization, Zhejiang University, Hangzhou, China.
CSIRO Agriculture and Food, Canberra, Australian Capital Territory, Australia.
Nat Genet. 2025 Jul 16. doi: 10.1038/s41588-025-02245-8.
With the looming challenges of climate change and population pressure, understudied cereals hold notably untapped potential for future global food security and sustainable agriculture due to their unique nutritional profiles and notable stress resilience. Multiomics holds great promise in realizing the value of understudied cereals by understanding the genetic basis and molecular mechanisms regulating their unique traits; however, multiomic studies of understudied cereals still lag behind those of major cereals, hindering their genetic improvement and wide adoption in modern agriculture. Here, we discuss the limitations and challenges in multiomic studies of understudied cereals and how they can be overcome to enhance utilization of the traits unique to understudied cereals in improving both themselves and major cereals. We also offer a database specific to understudied cereals, including multiomics data from 12 understudied cereals and wild relatives for some of these, to serve the community.
面对气候变化和人口压力等迫在眉睫的挑战，由于其独特的营养特性和显著的抗逆性，研究较少的谷物在未来全球粮食安全和可持续农业方面具有尚未开发的巨大潜力。多组学在通过了解调控这些独特性状的遗传基础和分子机制来实现研究较少谷物的价值方面具有巨大潜力；然而，对研究较少谷物的多组学研究仍落后于主要谷物，这阻碍了它们在现代农业中的遗传改良和广泛应用。在此，我们讨论了对研究较少谷物进行多组学研究的局限性和挑战，以及如何克服这些问题，以加强利用研究较少谷物的独特性状来改良它们自身以及主要谷物。我们还提供了一个专门针对研究较少谷物的数据库，其中包括来自12种研究较少谷物以及部分这些谷物野生近缘种的多组学数据，以供学界使用。
