Li Ying, Zhuang Ruixin, Zhang Jianhua, Liu Xiaojie
College of Sports Science, Jishou University, Jishou, Hunan, China.
School of Physical Education and Arts, Hunan University of Medicine, Huaihua, Hunan, China.
Front Neurol. 2025 Jul 2;16:1601080. doi: 10.3389/fneur.2025.1601080. eCollection 2025.
Reduced quality of life is a typical manifestation of Parkinson's disease (PD) patients, and exercise has a significant effect on improving the quality of life of PD patients. However, it is still unclear which exercise is effective in improving quality of life for people with Parkinson's disease. The aim of this study was to compare effective exercises for improving quality of life in patients with Parkinson's disease through a network meta-analysis.
We conducted comprehensive database searches, including PubMed, Cochrane Library, Embase, Web of Science and CNKI. The included studies assessed methodological quality using the Cochrane Bias risk tool, and we collected information from the studies to compare the effects of 25 exercise interventions on quality of life in PD patients.
The results of the network meta-analysis showed that QG is higher than OE (MD, -9.26; 95%CI, -18.25 to -0.27), FAE (MD, -10.77; 95%CI -19.52 to -2.02), VR (MD, -10.65; 95%CI -19.70 to -1.60), TC (MD, -11.06; 95%CI -21.32 to -0.81), CT (MD, -11.42; 95%CI -20.73 to -2.11), RT (MD, -11.60; 95%CI -20.72 to -2.49), CE (MD -12.50; 95%CI -24.47 to -0.52), GT (MD -13.10; 95%CI -24.67 to -1.52) to better improve quality of life in patients with PD. DE is superior to TR (SMD, -2.10; 95%CI -3.75 to -0.45), BT (SMD, -2.63; 95%CI -4.93 to -0.32), BDJ (SMD, -4.14; 95%CI -6.15 to -2.14), RT (SMD, -4.54; 95%CI -6.94 to -2.14), TC (SMD, -5.28; 95%CI -7.73 to -2.84) in reduce depression. ROT is superior to TR (MD, 6.17; 95%CI 0.57 to 11.77), in improving balance capacity.
Our study found that QG improved the quality of life in patients with PD better than other forms of exercise. DE is more effective than other exercises in reducing depression in PD patients. ROT is better at improving the balance of PD patients.
生活质量下降是帕金森病（PD）患者的典型表现，运动对改善PD患者的生活质量有显著效果。然而，对于帕金森病患者而言，哪种运动能有效改善生活质量仍不明确。本研究旨在通过网状Meta分析比较改善帕金森病患者生活质量的有效运动。
我们进行了全面的数据库检索，包括PubMed、Cochrane图书馆、Embase、科学网和中国知网。纳入的研究使用Cochrane偏倚风险工具评估方法学质量，我们从这些研究中收集信息，以比较25种运动干预对PD患者生活质量的影响。
网状Meta分析结果显示，气功（QG）在改善PD患者生活质量方面优于常规运动（OE）（MD，-9.26；95%CI，-18.25至-0.27）、功能性动作评估（FAE）（MD，-10.77；95%CI -19.52至-2.02）、虚拟现实（VR）（MD，-10.65；95%CI -19.70至-1.60）、太极拳（TC）（MD，-11.06；95%CI -21.32至-0.81）、有氧舞蹈（CT）（MD，-11.42；95%CI -20.73至-2.11）、韵律操（RT）（MD，-11.60；95%CI -20.72至-2.49）、交际舞（CE）（MD -12.50；95%CI -24.47至-0.52）、高尔夫运动（GT）（MD -13.10；95%CI -24.67至-1.52）。在减轻抑郁方面，舞蹈运动（DE）优于传统康复训练（TR）（SMD，-2.10；95%CI -3.75至-0.45）、拳击训练（BT）（SMD，-2.63；95%CI -4.93至-0.32）、篮球运动（BDJ）（SMD，-4.14；95%CI -6.15至-2.14）、韵律操（RT）（SMD，-4.54；95%CI -6.94至-2.14）、太极拳（TC）（SMD，-5.28；95%CI -7.73至-2.84）。在改善平衡能力方面，旋转训练（ROT）优于传统康复训练（TR）（MD，6.17；95%CI 0.57至11.77）。
我们的研究发现，气功在改善PD患者生活质量方面优于其他形式的运动。舞蹈运动在减轻PD患者抑郁方面比其他运动更有效。旋转训练在改善PD患者平衡能力方面效果更佳。
