Estefany Villa-Aguilar, Karen Marín-Morales, Citlali Ayala-Galvan, Ailema Gonzalez-Ortiz, Jose Francisco Gonzalez-Zamora
Centro de Investigación Traslacional, Instituto Nacional de Pediatría, Mexico City, Mexico.
Front Pediatr. 2025 Jul 2;13:1591200. doi: 10.3389/fped.2025.1591200. eCollection 2025.
Appendicitis is the most common abdominal emergency in pediatrics and is suggested as a quality indicator for timely access to care in time-sensitive conditions. Despite advances in diagnostics, the incidence of complicated appendicitis (CA) remains high due to delays in pediatric surgical care, which can increase disease severity. Social vulnerability has been associated with surgical access, particularly in low- and middle-income populations. This study examines the relationship between surgical delay and social determinants of complicated appendicitis in children without social security in the Metropolitan Zone of México.
This retrospective cohort study was conducted in a pediatric public hospital. Consecutive cases from 2018 to 2021 with confirmed appendicitis diagnoses were included. The primary outcome variable was the type of appendicitis (acute/complicated), while two independent variables were the time of evolution (patient and hospital timing) and socioeconomic factors associated with social vulnerability. A logistic regression analysis assessed the relationship between appendicitis type and covariates.
A total of 943 pediatric cases of appendicitis were included. Out of these, 62.67% presented CA, with a mean age 10 ± 4 years. 60.9% were well-nourished, and 16% had at least one comorbidity. Most subjects (76%) met at least two criteria for social vulnerability, and 74.7% of families held unskilled jobs. The median symptom-to-admission time was 2 days, with a median hospital-to-surgery time of 19.5 h (p25-p75). Prehospital delays affected 57.8% of cases ( = 545), and 39% ( = 365) experienced intrahospital delays. In the multivariable logistic regression, prehospital delay ≥48 h (OR 3.27, 95% CI 2.43-4.39) and children under 5 years (OR 1.76, 95% CI 1.09-2.84) were associated with higher odds of CA.
The high frequency of CA in uninsured children at a public hospital is due to surgical delays of two or more days. Social vulnerabilities, as observed globally, hinder access to quality care. Thus, appendicitis should be recognized as both a medical and social issue, requiring a comprehensive approach that addresses social vulnerability.
阑尾炎是儿科最常见的腹部急症,被视为在对时间敏感的情况下及时获得治疗的质量指标。尽管诊断技术有所进步,但由于儿科手术治疗的延迟,复杂性阑尾炎(CA)的发病率仍然很高,这会增加疾病的严重程度。社会脆弱性与手术可及性相关,尤其是在低收入和中等收入人群中。本研究探讨了墨西哥大都会区无社会保障儿童复杂性阑尾炎的手术延迟与社会决定因素之间的关系。
本回顾性队列研究在一家儿科公立医院进行。纳入2018年至2021年确诊为阑尾炎的连续病例。主要结局变量是阑尾炎类型(急性/复杂性),两个独立变量是病情发展时间(患者和医院时间)以及与社会脆弱性相关的社会经济因素。逻辑回归分析评估了阑尾炎类型与协变量之间的关系。
共纳入943例儿科阑尾炎病例。其中,62.67%为复杂性阑尾炎,平均年龄10±4岁。60.9%营养良好,16%至少有一种合并症。大多数受试者(76%)至少符合两项社会脆弱性标准,74.7%的家庭从事非技术性工作。症状出现到入院的中位时间为2天,医院到手术的中位时间为19.5小时(第25百分位数至第75百分位数)。院前延迟影响了57.8%的病例(n = 545),39%(n = 365)经历了院内延迟。在多变量逻辑回归中,院前延迟≥48小时(比值比3.27,95%置信区间2.43 - 4.39)和5岁以下儿童(比值比1.76,95%置信区间1.09 - 2.84)与复杂性阑尾炎的较高发病几率相关。
公立医院中无保险儿童复杂性阑尾炎的高发病率是由于手术延迟两天或更长时间所致。正如全球所观察到的,社会脆弱性阻碍了获得优质医疗服务的机会。因此,阑尾炎应被视为一个医学和社会问题,需要采取综合方法来解决社会脆弱性问题。