Raj Preethi S, Bergfeld Wilma F, Belsito Donald V, Cohen David E, Klaassen Curtis D, Liebler Daniel C, Marks James G, Peterson Lisa A, Shank Ronald C, Slaga Thomas J, Snyder Paul W, Fiume Monice M, Heldreth Bart
Cosmetic Ingredient Review Former Senior Scientific Analyst/Writer.
Expert Panel for Cosmetic Ingredient Safety Member.
Int J Toxicol. 2025 Aug;44(2_suppl):92S-102S. doi: 10.1177/10915818251342562. Epub 2025 Jul 17.
The Expert Panel for Cosmetic Ingredient Safety (Panel) assessed the safety of Hydroxy Tetramethylpiperidine Oxide and Tris(Tetramethylhydroxypiperidinol) Citrate as used in cosmetic formulations. These ingredients are reported to function as an antioxidant and a light stabilizer, respectively. The Panel considered the available data and concluded that Hydroxy Tetramethylpiperidine Oxide and Tris(Tetramethylhydroxypiperidinol) Citrate are safe in cosmetics in the present practices of use and concentration described in this safety assessment.
化妆品成分安全专家小组（小组）评估了化妆品配方中使用的羟基四甲基哌啶氧化物和柠檬酸三（四甲基羟基哌啶醇）的安全性。据报道，这些成分分别起抗氧化剂和光稳定剂的作用。小组审议了现有数据，并得出结论，在本安全评估所述的当前使用方法和浓度下，羟基四甲基哌啶氧化物和柠檬酸三（四甲基羟基哌啶醇）在化妆品中是安全的。
