Yan Lingjun, Xie Bingqin, Li Yanfen, Liu Zilin, Huang Yu, He Baochang, Qiu Yu, Luo Lan, Yan Fuhua, Chen Fa
Department of Neurosurgery, Neurosurgery Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Department of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, China.
J Periodontol. 2025 Jul 17. doi: 10.1002/JPER.24-0638.
This study aimed to provide an updated assessment of the global, regional, and national burden of oral disorders from 1990 to 2021, and forecast trends for the next 30 years.
Data on incidence, prevalence, and disability-adjusted life years (DALYs) were extracted from the Global Burden of Diseases(GBD) 2021. The changing trends in the burden of oral disorders and subtypes were estimated using percentage change. The Nordpred model based on the age-period-cohort analysis was used to predict the burden of oral disorders over the next 30 years.
From 1990 to 2021, all oral disorders exhibited a 35.54% incidence, reaching 3.74 billion cases. Regional analysis revealed that Tropical Latin America and Southeast Asia had higher age-standardized incidence rates(ASIR). Dental caries in permanent teeth increased by 6.0% in the ASIR, while deciduous teeth caries declined by 7.83%. Periodontal disease incidence surged by 76.32% to 89.6 million cases, with discrepancies between sexes-1.05% decrease in males and a 1.14% increase in females. Edentulism incidence rose dramatically by 93.56%, totaling 26.5 million cases. Projections for the next 30 years suggest a continued rise in oral disorder cases, with the ASIR expected to rise, particularly in periodontal diseases.
The rising global burden of oral disorders, notably periodontal diseases, remains a significant public health challenge. Factors such as poor oral hygiene and disparities in healthcare access might contribute to these trends. Targeted preventive measures, including community education and alongside partnerships between researchers and policy-makers, are crucial for mitigating their impact on public health.
Our study examines the increasing global impact of oral diseases from 1990 to 2021 and predicts their trajectory over the next 30 years. We analyzed data on how often these conditions occur and the years of healthy life lost due to them. Overall, we found that oral disorders affected an alarming 3.74 billion people by 2021, with regions like Tropical Latin America and Southeast Asia showing particularly high rates. Notably, dental cavities in adult teeth grew by 6%, while those in children's teeth declined. However, gum disease and tooth loss saw significant increases-gum disease cases shot up by over 76%, with a notable rise among women. Looking ahead, we expect more people to suffer from oral disorders, particularly gum disease. This is a serious issue for public health, possibly driven by factors like poor dental care and unequal access to services. Addressing this requires focused efforts, such as educating communities and improving access to dental care, alongside collaboration between researchers and health officials to lessen the burden of these conditions on people's lives.
本研究旨在对1990年至2021年全球、区域和国家口腔疾病负担进行最新评估，并预测未来30年的趋势。
从《2021年全球疾病负担》（GBD）中提取发病率、患病率和伤残调整生命年（DALYs）数据。使用百分比变化估计口腔疾病及其亚型负担的变化趋势。基于年龄-时期-队列分析的Nordpred模型用于预测未来30年口腔疾病负担。
1990年至2021年，所有口腔疾病的发病率上升了35.54%，达到37.4亿例。区域分析显示，热带拉丁美洲和东南亚的年龄标准化发病率（ASIR）较高。恒牙龋齿的ASIR上升了6.0%，而乳牙龋齿下降了7.83%。牙周病发病率激增76.32%，达到8960万例，存在性别差异——男性下降1.05%，女性上升1.14%。无牙症发病率急剧上升93.56%，总计2650万例。未来30年的预测表明口腔疾病病例将持续增加，ASIR预计上升，尤其是在牙周病方面。
全球口腔疾病负担不断上升，尤其是牙周病，仍然是一项重大的公共卫生挑战。口腔卫生差和医疗服务获取不平等可能是导致这些趋势的因素。有针对性的预防措施，包括社区教育以及研究人员与政策制定者之间的合作，对于减轻其对公共卫生的影响至关重要。
我们的研究考察了1990年至2021年口腔疾病对全球日益增加的影响，并预测了未来30年它们的发展轨迹。我们分析了这些疾病的发生频率以及因它们而损失的健康生命年数的数据。总体而言，我们发现到2021年口腔疾病影响了多达37.4亿人，令人担忧，热带拉丁美洲和东南亚等地区的发病率尤其高。值得注意的是，恒牙龋齿增加了6%，而儿童牙齿龋齿减少。然而，牙龈疾病和牙齿脱落显著增加——牙龈疾病病例激增超过76%，女性中尤为明显。展望未来，我们预计会有更多人患口腔疾病，尤其是牙龈疾病。这对公共卫生是一个严重问题，可能是由口腔护理差和服务获取不平等之类的因素导致的。解决这个问题需要集中努力，比如开展社区教育和改善口腔护理服务获取，以及研究人员与卫生官员之间的合作，以减轻这些疾病对人们生活的负担。
