Wang Weiguang, Ma Lijuan, Cai Wei, Zhao Haiyan, Zhang Xia
School of Computer Science and Engineering, Northeastern University, Shenyang, 110819, Liaoning, China; Neusoft Research of Intelligent Healthcare Technology, Co. Ltd, Shenyang, 110167, Liaoning, China.
Neusoft Research of Intelligent Healthcare Technology, Co. Ltd, Shenyang, 110167, Liaoning, China.
Artif Intell Med. 2025 Oct;168:103188. doi: 10.1016/j.artmed.2025.103188. Epub 2025 Jul 11.
Medical entity alignment is crucial for the integration and reasoning of medical knowledge, aiming to match semantically equivalent entities across different medical knowledge graphs. Unlike entities in general knowledge graphs, medical entities contain rich multi-aspect information, which not only includes structural and attribute information but also additional information such as ontology and descriptions. However, existing entity alignment methods overlook these additional pieces of information and lack exploration into the fusion of multi-aspect information. This leads to less-than-ideal performance in medical entity alignment. To address the aforementioned issues, in this paper, we propose a hierarchical medical knowledge graph entity alignment method, termed HMEA, which integrates multi-aspect information. Firstly, we represent the medical knowledge graph as a hierarchical heterogeneous graph to model the multi-aspect information of medical entities. Secondly, we design different representation learning methods according to the characteristics of multi-aspect information to obtain vector representations of entities in different dimensions. Subsequently, we devise a two-stage multi-aspect knowledge fusion mechanism to dynamically integrate multi-aspect information, enabling mutual complementarity. Finally, we utilize the fused entity vector representations to guide entity alignment. We compare our approach with state-of-the-art baseline models on ten different types of publicly available datasets and further conduct ablation and parameter analyses. Experimental results validate the effectiveness and robustness of the proposed model. In benchmark tests across all datasets, HMEA outperforms the current state-of-the-art methods significantly.
医学实体对齐对于医学知识的整合与推理至关重要,旨在匹配不同医学知识图谱中语义等价的实体。与一般知识图谱中的实体不同,医学实体包含丰富的多方面信息,不仅包括结构和属性信息,还包括诸如本体和描述等附加信息。然而,现有的实体对齐方法忽略了这些附加信息,并且缺乏对多方面信息融合的探索。这导致医学实体对齐的性能不尽如人意。为了解决上述问题,在本文中,我们提出了一种分层医学知识图谱实体对齐方法,称为HMEA,该方法整合了多方面信息。首先,我们将医学知识图谱表示为分层异构图,以对医学实体的多方面信息进行建模。其次,我们根据多方面信息的特征设计不同的表示学习方法,以获得不同维度的实体向量表示。随后,我们设计了一个两阶段的多方面知识融合机制,以动态整合多方面信息,实现相互补充。最后,我们利用融合后的实体向量表示来指导实体对齐。我们在十种不同类型的公开可用数据集上,将我们的方法与最先进的基线模型进行了比较,并进一步进行了消融和参数分析。实验结果验证了所提出模型的有效性和鲁棒性。在所有数据集的基准测试中,HMEA显著优于当前最先进的方法。