Pennings Guido, Lassen Emilie, Lemmen Josephine G, Skytte Anne-Bine
Department of Philosophy and Moral Science, Bioethics Institute Ghent (BIG), Universiteit Gent, Ghent, Belgium.
Cryos International Sperm & Egg Bank, Aarhus, Denmark.
J Assist Reprod Genet. 2025 Jul 17. doi: 10.1007/s10815-025-03588-1.
The study intended to find out whether sperm and egg donors hold different views on identifiability, information about donor offspring, genetic testing, and extended carrier screening.
An online questionnaire was sent to accepted sperm (n = 70) and egg donors (n = 39) from the same gamete bank in the United States 3 years apart (2020 and 2023). Only questions that were identical for both groups were included in the analysis.
There were no differences in the donors' reasons for donating: both groups were mainly motivated by the wish to help childless couples, to earn money or a combination of the two. The study was performed in a setting where donors could choose between identity (ID) release or non-ID release donation. Egg donors were equally likely to opt for ID release (69.2%) as sperm donors (73.7%). The only significant difference was that egg donors were more likely than sperm donors to want to know whether the donation resulted in a pregnancy or birth (89.7% vs. 68.4%, p = 0.02). No differences were found in the information they wanted to receive about the offspring. They were also equally likely to be open about their donor status with other people and their own children. Both groups were in favour of genetic testing (92.6% and 82%, respectively) and positive about extended carrier screening (87.2 and 76.3%, respectively).
There were few differences in the views and attitudes of egg and sperm donors regarding identity release, information about donor offspring, and extended genetic testing.
本研究旨在探究精子和卵子捐赠者在可识别性、捐赠者后代信息、基因检测以及扩展携带者筛查方面是否持有不同观点。
分别向美国同一家配子库在2020年和2023年接受的精子捐赠者（n = 70）和卵子捐赠者（n = 39）发送在线问卷。分析仅纳入两组相同的问题。
捐赠者的捐赠原因没有差异：两组的主要动机都是希望帮助无子女夫妇、赚钱或两者兼有。该研究是在捐赠者可以选择公开身份（ID）或不公开身份捐赠的背景下进行的。卵子捐赠者选择公开身份的可能性（69.2%）与精子捐赠者（73.7%）相同。唯一显著的差异是，卵子捐赠者比精子捐赠者更想知道捐赠是否导致怀孕或分娩（89.7%对68.4%，p = 0.02）。在他们希望获得的关于后代的信息方面没有发现差异。他们向他人和自己的孩子公开捐赠者身份的可能性也相同。两组都赞成基因检测（分别为92.6%和82%），并且对扩展携带者筛查持积极态度（分别为87.2%和76.3%）。
卵子和精子捐赠者在身份公开、捐赠者后代信息以及扩展基因检测的观点和态度上几乎没有差异。
