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利用媒体加强初级保健中儿科患者参与研究的招募工作。

Using media to enhance paediatric patient recruitment for research in primary care.

作者信息

Ganzevoort Ilse N, Berger Marjolein Y, Benninga Marc A, Vlieger Arine M, Holtman Gea A

机构信息

Department of Primary and Long-term Care, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Department of Pediatrics, Emma Children's Hospital, Amsterdam University Medical Center, Amsterdam, The Netherlands.

出版信息

Prim Health Care Res Dev. 2025 Jul 18;26:e62. doi: 10.1017/S1463423625100315.

Abstract

Recruitment of participants for research is often difficult in primary care, especially children and adolescents. Poor recruitment often leads to extension or discontinuation of randomized controlled trials involving patients. This study describes the impact of media recruitment compared to recruitment via general practitioners (GPs) on characteristics of 152 children aged 7-17 years with functional abdominal pain (FAP) and irritable bowel syndrome. Demographics, clinical and psychosocial characteristics were compared. No clinically relevant differences were found, except for longer pain symptom duration and more diagnoses of FAP in children recruited via media compared to children recruited by their GP. Our results suggest that recruitment via media is effective to recruit children in primary care without inducing relevant baseline characteristic differences and this might decrease research recruitment load for GPs. Subgroup analyses on recruitment method are recommended because recruitment strategy might induce differences in unknown baseline characteristics between groups.

摘要

在基层医疗中,招募研究参与者往往很困难,尤其是儿童和青少年。招募不佳常常导致涉及患者的随机对照试验延期或终止。本研究描述了与通过全科医生(GP)招募相比,媒体招募对152名7至17岁功能性腹痛(FAP)和肠易激综合征儿童特征的影响。比较了人口统计学、临床和心理社会特征。除了与通过全科医生招募的儿童相比,通过媒体招募的儿童疼痛症状持续时间更长且FAP诊断更多外,未发现临床相关差异。我们的结果表明,通过媒体招募在基层医疗中招募儿童是有效的,不会引起相关基线特征差异,这可能会减轻全科医生的研究招募负担。建议对招募方法进行亚组分析,因为招募策略可能会导致组间未知基线特征的差异。

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