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通过杂交测序获得与对虾幼体急性肝胰腺坏死病(AHPND)相关的L2171和L2181菌株的全基因组序列。

Complete genome sequences of strains L2171 and L2181 associated with AHPND in postlarvae by hybrid sequencing.

作者信息

Reyes Guillermo, Andrade Betsy, Betancourt Irma, Bayot Bonny

机构信息

Centro Nacional de Acuicultura e Investigaciones Marinas, CENAIM, Escuela Superior Politécnica del Litoral, ESPOL, Guayaquil, Ecuador.

Facultad de Ingeniería Marítima y Ciencias del Mar, FIMCM, Escuela Superior Politécnica del Litoral, ESPOL, Guayaquil, Ecuador.

出版信息

Data Brief. 2025 Jun 22;61:111819. doi: 10.1016/j.dib.2025.111819. eCollection 2025 Aug.

DOI:10.1016/j.dib.2025.111819
PMID:40677256
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12269462/
Abstract

strains L2171 and L2181 were isolated from a shrimp hatchery. Both strains carry the pVA plasmid harboring the genes encoding the binary PirAB toxins that cause the acute hepatopancreatic necrosis disease (AHPND) in cultured shrimp. The strains also harbor multidrug resistance (MDR) and a repertoire of virulence factor genes. Our goal was to determine their complete genome sequences and perform a comprehensive analysis of their genetic characteristics. Therefore, the genomes of two strains, which are highly virulent to shrimp were sequenced by Illumina and the PacBio platforms. These data contribute to a better understanding of and its role as a pathogen in commercially important species such as farmed shrimp, providing valuable insights for disease management in aquaculture.

摘要

L2171和L2181菌株是从一家对虾育苗场分离出来的。这两种菌株都携带pVA质粒,该质粒含有编码二元PirAB毒素的基因,这些毒素会在养殖对虾中引发急性肝胰腺坏死病(AHPND)。这些菌株还具有多重耐药性(MDR)和一系列毒力因子基因。我们的目标是确定它们的完整基因组序列,并对其遗传特征进行全面分析。因此,通过Illumina和PacBio平台对两种对虾具有高毒力的菌株的基因组进行了测序。这些数据有助于更好地了解其作为养殖对虾等重要商业物种病原体的情况,并为水产养殖疾病管理提供有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e14/12269462/b89c443de24b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e14/12269462/38c16d70ecfb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e14/12269462/b89c443de24b/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e14/12269462/38c16d70ecfb/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e14/12269462/b89c443de24b/gr2.jpg

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