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日光暴露皮肤扁平苔藓与鳞状细胞癌并存:一例报告

Coexistence of Lichen Planus and Squamous Cell Carcinoma on Sun-Exposed Skin: A Case Report.

作者信息

Velikova Adelina, Bekyarova Anastasia I, Kirilova Andreya, Naydenova Kristina, Stoyanov George S, Popov Hristo

机构信息

General and Clinical Pathology, Forensic Medicine and Deontology, Medical University - Varna, Varna, BGR.

Pathology, Multiprofile Hospital for Active Treatment, Shumen, BGR.

出版信息

Cureus. 2025 Jun 17;17(6):e86194. doi: 10.7759/cureus.86194. eCollection 2025 Jun.

Abstract

Lichen planus (LP) is a chronic idiopathic skin disorder that has a predilection for sun-exposed areas. Although rare, there is a possibility that chronic LP lesions could progress to squamous cell carcinoma (SCC), a non-melanocytic malignant skin neoplasm. Cumulative exposure to ultraviolet radiation, particularly in individuals with lighter skin tones, is one of the leading risk factors for cutaneous SCC (cSCC). In this report, we present a case of a 79-year-old male patient who was diagnosed with a moderately differentiated cSCC with facial localization. This condition developed on the background of preexisting actinic keratosis, and was accompanied by a LP.

摘要

扁平苔藓(LP)是一种慢性特发性皮肤病,好发于暴露于阳光下的部位。虽然罕见,但慢性LP病变有可能进展为鳞状细胞癌(SCC),这是一种非黑素细胞性皮肤恶性肿瘤。累积暴露于紫外线辐射,尤其是肤色较浅的个体,是皮肤SCC(cSCC)的主要危险因素之一。在本报告中,我们介绍了一例79岁男性患者,他被诊断为面部局限性中度分化的cSCC。这种情况是在先前存在的光化性角化病的基础上发展而来的,并伴有LP。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac33/12270506/4611c68a784f/cureus-0017-00000086194-i01.jpg

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