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1例罕见的耳前区毛母质瘤新病例及病例系列回顾

A new case of the pilomatrixoma rare in the preauricular region and review of series of cases.

作者信息

Pinheiro Tiago Novaes, Fayad Flavio Têndolo, Arantes Pedro, Benetti Francine, Guimarães Gustav, Cintra Luciano Tavares Angelo

机构信息

Oral Pathology and Oral Medicine, Amazonas State University, Manaus, AM, 69050-010, Brazil.

Maxilofacial Surgery, Amazonas State University, Manaus, AM, 69050-010, Brazil.

出版信息

Oral Maxillofac Surg. 2018 Dec;22(4):483-488. doi: 10.1007/s10006-018-0724-8. Epub 2018 Oct 3.

DOI:10.1007/s10006-018-0724-8
PMID:30284072
Abstract

Pilomatrixoma is considered a rare benign tumor arising from the hair follicle, most common in the head and neck region, but it is rarely diagnosed on a clinical basis. This report describes a new case of giant pilomatrixoma in a 36-year-old female patient. The nodule was localized in the preauricular area on the right side, appearing as a slow-growing, fixed, painless, with a hardened consistency, unusual giant (4.5 cm). A cone-beam computed tomography (CBCT) examination showed a slightly hyperdense lesion, and fine-needle aspiration cytology (FNAC) revealed peripheral blood and mononucleated inflammatory cells. After enucleation of lesion, a diagnosis of pilomatrixoma was confirmed. The differential diagnosis of pilomatrixoma is broad, because its characteristics also can be found in other lesions common to the head and neck. Thus, a lesion in the head and neck, adherent to the skin, and well demarcated, mainly in the young and in females, should be suspected as pilomatrixoma.

摘要

毛母质瘤被认为是一种罕见的起源于毛囊的良性肿瘤,最常见于头颈部区域,但临床上很少能确诊。本报告描述了一名36岁女性患者的巨大毛母质瘤新病例。结节位于右侧耳前区,表现为生长缓慢、固定、无痛、质地硬,为罕见的巨大型(4.5厘米)。锥形束计算机断层扫描(CBCT)检查显示病变稍高密度,细针穿刺细胞学检查(FNAC)显示有外周血和单核炎性细胞。病变摘除后,确诊为毛母质瘤。毛母质瘤的鉴别诊断范围广泛,因为其特征也可见于头颈部其他常见病变。因此,对于头颈部附着于皮肤、边界清晰、主要发生于年轻人和女性的病变,应怀疑为毛母质瘤。

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本文引用的文献

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A Rare Case of Pilomatrixoma (Calcifying Epithelioma of Malherbe) of Parotid Space Masquerading as Salivary Gland Tumor.一例伪装成唾液腺肿瘤的腮腺间隙毛母质瘤(马勒布钙化上皮瘤)罕见病例。
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Pilomatricoma Associated with Kabuki Syndrome.
Pediatr Dermatol. 2017 Jan;34(1):e26-e27. doi: 10.1111/pde.13014. Epub 2016 Oct 25.
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IL-8, IL-8RA (CXCR1) and IL-8RB (CXCR2) expression in pilomatricoma.
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儿童耳垂毛母质瘤:临床特征与手术治疗
Am J Case Rep. 2025 May 22;26:e946474. doi: 10.12659/AJCR.946474.
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Atypical giant proliferating cystic pilomatrixoma: A case review.非典型巨大增殖性囊性毛母质瘤:病例回顾
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Atypical Pediatric Presentation of Pilomatricoma.毛母质瘤的非典型儿科表现。
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Keloid-like Pilomatricoma of the Auricle: A Case Report and Review of Literature.耳廓瘢痕疙瘩样毛母质瘤:1例报告并文献复习
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Pilomatrixoma Recurring as Giant Form.复发性巨大型毛母质瘤
Cureus. 2022 Jan 17;14(1):e21308. doi: 10.7759/cureus.21308. eCollection 2022 Jan.
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Pilomatrixoma is a diagnostic trap in fine-needle aspiration cytology of the parotid region.
毛母质瘤在腮腺区细针穿刺细胞学检查中是一个诊断陷阱。
Diagn Cytopathol. 2016 Jun;44(6):516-8. doi: 10.1002/dc.23466. Epub 2016 Mar 16.
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