Kobayashi Shinichiro, Muta Yuki, Murakami Shunsuke, Kanetaka Kengo
Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.
World J Gastrointest Endosc. 2025 Jul 16;17(7):108289. doi: 10.4253/wjge.v17.i7.108289.
Xu retrospectively assessed endoscopic resection (ER) for esophageal gastrointestinal stromal tumors (E-GISTs) and reported excellent 5-year survival rates. Although ER shows promise as a minimally invasive procedure, the 75% R0 resection rate with recurrence observed even after R0 resection warrants further discussion. We highlight the need for careful patient selection based on tumor size, location, and risk, considering endoscopic and thoracoscopic approaches. Future studies should refine ER techniques, optimize patient selection, and establish long-term follow-up to guide E-GIST management.
徐回顾性评估了食管胃肠道间质瘤(E-GISTs)的内镜切除术(ER),并报告了出色的5年生存率。尽管ER作为一种微创手术显示出前景,但即使在R0切除术后仍观察到75%的R0切除率伴有复发,这值得进一步讨论。我们强调,基于肿瘤大小、位置和风险,考虑内镜和胸腔镜方法,需要谨慎选择患者。未来的研究应改进ER技术,优化患者选择,并建立长期随访以指导E-GIST的管理。