Redfors Ylva Dahlin, Björsne Andreas, Finizia Caterina
Department of Otorhinolaryngology, Head and Neck Surgery Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg Gothenburg Sweden.
Department of Otorhinolaryngology, Head and Neck Surgery Region Västra Götaland, Sahlgrenska University Hospital Gothenburg Sweden.
Laryngoscope Investig Otolaryngol. 2025 Jul 16;10(4):e70198. doi: 10.1002/lio2.70198. eCollection 2025 Aug.
The aim of this study was to assess the presentation of otosclerosis in subjects with newly developed hearing loss.
This study was part of a prospective study that included subjects with newly diagnosed otosclerosis with the intention to undergo treatment. For comparison, statistical data from the Public Health Agency of Sweden and Statistics Sweden (SCB) were used. The subjects answered questionnaires covering demographic data, the Short Form SF 36 (SF-36), the Glasgow Hearing Aid Benefit Profile (GHABP) and the Hospital Anxiety and Depression Scale (HADS). Pure tone and speech audiometry were performed.
One hundred and fifty-eight subjects were included, of whom 62% were women. The mean age was 45.8 years, and women were significantly younger than men were ( value 0.001). Tinnitus was reported by 72%, which was significantly greater than that reported by the general population. The study population had a high level of health-related quality of life. Hearing disability was most often displayed in more challenging listening situations, such as engaging in conversations with several people. The mean hearing level was of moderate severity (mean PTA AC 48 dB HL), with unilateral hearing loss in most cases (bilateral hearing loss; female 32% and male 25%).
The otosclerosis cohort had a high level of quality of life despite experiencing hearing disability, especially in challenging listening situations, and a high level of tinnitus when seeking help.
本研究旨在评估新发听力损失患者耳硬化症的表现。
本研究是一项前瞻性研究的一部分，纳入了新诊断为耳硬化症且打算接受治疗的患者。为作比较，使用了瑞典公共卫生署和瑞典统计局（SCB）的统计数据。受试者回答了涵盖人口统计学数据、简短健康调查问卷SF-36、格拉斯哥助听器效益量表（GHABP）和医院焦虑抑郁量表（HADS）的问卷。进行了纯音和言语测听。
共纳入158名受试者，其中62%为女性。平均年龄为45.8岁，女性明显比男性年轻（ 值0.001）。72%的受试者报告有耳鸣，这显著高于普通人群的报告率。研究人群的健康相关生活质量较高。听力残疾最常出现在更具挑战性的听力情境中，比如与几个人交谈时。平均听力水平为中度严重程度（平均气导纯音听阈48dB HL），大多数情况下为单侧听力损失（双侧听力损失；女性32%，男性25%）。
尽管存在听力残疾，尤其是在具有挑战性的听力情境中，且在寻求帮助时耳鸣程度较高，但耳硬化症患者队列的生活质量较高。
3级。
