Wu Jian, Chen Yue, Miao Yudong, Li Quanman, Tarimo Clifford Silver, Dai Nengguang, Zhao Qiuping, Niu Yadong
Department of Health Management, College of Public Health, Zhengzhou University, Zhengzhou, China.
Department of Science and Laboratory Technology, Dar es Salaam Institute of Technology, Dar es Salaam, Tanzania.
Front Public Health. 2025 Jul 3;13:1610715. doi: 10.3389/fpubh.2025.1610715. eCollection 2025.
This study aimed to examine the association between lifestyle behaviors and body mass index (BMI) along with their potential interactions with the severity of blood pressure (BP) classifications among older adults with hypertension.
Among 17,441 participants, lifestyle behaviors were assessed, including smoking, drinking, dietary patterns, physical activity, and sleeping. Multinomial logistic regression was used to examine the association between lifestyle behaviors and BMI with BP classifications, and multiplicative interactions were included to estimate potential interactions. To explore variations, analyses were also stratified by BMI.
High-risk dietary pattern and obesity were negatively associated with lower BP classifications, with odds ratios (ORs) and 95% confidence intervals (CIs) for normal BP, high-normal BP, and grade 1 hypertension in high-risk dietary pattern were 0.74 (0.57-0.95), 0.69 (0.54-0.90), 0.75 (0.59-0.95), and the ORs (95% CIs) in obesity were 0.61 (0.53-0.69), 0.77 (0.67-0.89), 0.82 (0.73-0.93). Compared with never drinking, former drinkers had higher odds of having normal BP (OR: 1.45, 95% CI: 1.15-1.82), high-normal BP (OR: 1.31, 95% CI: 1.02-1.67), and grade 1 hypertension (OR: 1.26, 95% CI: 1.01-1.58). The multiplicative interaction between drinking status and BMI was found on BP classifications ( <0.05), and the effects of former drinking and low PA level on BP control were significant in overweight and underweight groups, respectively ( < 0.05).
Poor diet and obesity are associate with severe BP, particularly among non-drinking older adults, suggesting targeted interventions in rural primary care.
本研究旨在探讨生活方式行为与体重指数(BMI)之间的关联,以及它们在老年高血压患者中与血压(BP)分级严重程度的潜在相互作用。
在17441名参与者中,评估了生活方式行为,包括吸烟、饮酒、饮食模式、身体活动和睡眠。采用多项逻辑回归分析生活方式行为和BMI与血压分级之间的关联,并纳入乘法交互作用以估计潜在的相互作用。为了探索差异,分析还按BMI进行了分层。
高风险饮食模式和肥胖与较低的血压分级呈负相关,高风险饮食模式下正常血压、高正常血压和1级高血压的比值比(OR)及95%置信区间(CI)分别为0.74(0.57 - 0.95)、0.69(0.54 - 0.90)、0.75(0.59 - 0.95),肥胖情况下的OR(95%CI)分别为0.61(0.53 - 0.69)、0.77(0.67 - 0.89)、0.82(0.73 - 0.93)。与从不饮酒者相比,既往饮酒者血压正常(OR:1.45,95%CI:1.15 - 1.82)、高正常血压(OR:1.31,95%CI:1.02 - 1.67)和1级高血压(OR:1.26,95%CI:1.01 - 1.58)的几率更高。发现饮酒状态与BMI之间在血压分级上存在乘法交互作用(<0.05),既往饮酒和低身体活动水平对血压控制的影响分别在超重和体重不足组中显著(<0.05)。
不良饮食和肥胖与严重血压相关,尤其是在不饮酒的老年人中,这表明在农村初级保健中需要有针对性的干预措施。