Cernasev Alina, Scott Devin, Eckert Becka, Jasmin Hilary, Axon David R
Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center College of Pharmacy, 301 S. Perimeter Park Dr., Suite 220, Nashville, TN 37211, United States of America.
Teaching and Learning Center, University of Tennessee Health Science Center, 920 Madison, Suite 424, Memphis, TN 38163, United States of America.
Explor Res Clin Soc Pharm. 2025 Jun 24;19:100625. doi: 10.1016/j.rcsop.2025.100625. eCollection 2025 Sep.
Deprescribing is increasingly investigated through a qualitative lens, yet no evidence synthesis of the extant qualitative deprescribing literature exists. This study aimed to identify and synthesize relevant qualitative data about the role of the pharmacist or pharmacy profession in deprescribing in the United States.
A systematic literature review was conducted in July 2024 in MEDLINE (PubMed), Scopus (Elsevier), and Embase (Elsevier). The primary search concepts included terms around pill burden, cessation and de-prescription, as well as a search string to narrow results to qualitative reports. From 4410 unique records after deduplication, 46 abstracts were included for full text review.
After full text review, 11 records were deemed suitable for inclusion in this review. Three used interviews, five used focus groups, and three used both. Three studies used the theory of planned behavior, two studies used the capability, opportunity, and motivation behavior model, one used the chronic care model, one used the interprofessional shared decision-making model, one used grounded theory, and three did not use a framework. Studies were conducted in New York ( = 3), Arizona, Maine, and Tennessee ( = 3), California ( = 1), Iowa ( = 1), Massachusetts ( = 1), North Carolina ( = 1), and Rhode Island ( = 1). Key themes identified across the studies included enablers, obstacles, process of deprescribing, and deprescribing in pharmacy education.
Deprescribing is a complex process that involves the entire healthcare team, including pharmacists who have unique expertise to support the team through education and information about medication and disease states.
通过定性研究视角对减药（停药）的研究日益增多，但目前尚无对现有定性减药文献的证据综合分析。本研究旨在识别和综合关于美国药剂师或药学专业在减药（停药）中作用的相关定性数据。
2024年7月在MEDLINE（PubMed）、Scopus（爱思唯尔）和Embase（爱思唯尔）中进行了系统的文献综述。主要搜索概念包括围绕用药负担、停药和减药的术语，以及将结果缩小到定性报告的搜索字符串。在去重后的4410条独特记录中，46篇摘要被纳入全文审查。
经过全文审查，11条记录被认为适合纳入本综述。三项研究使用了访谈，五项使用了焦点小组，三项同时使用了两者。三项研究使用了计划行为理论，两项研究使用了能力、机会和动机行为模型，一项使用了慢性病护理模型，一项使用了跨专业共同决策模型，一项使用了扎根理论，三项未使用框架。研究在纽约（n = 3）、亚利桑那州、缅因州和田纳西州（n = 3）、加利福尼亚州（n = 1）、爱荷华州（n = 1）、马萨诸塞州（n = 1）、北卡罗来纳州（n = 1）和罗德岛州（n = 1）进行。各项研究中确定的关键主题包括促成因素、障碍、减药（停药）过程以及药学教育中的减药（停药）。
减药（停药）是一个复杂的过程，涉及整个医疗团队，包括药剂师，他们拥有独特的专业知识，可通过提供有关药物和疾病状态的教育和信息来支持该团队。
