Sağmak Tartar Ayşe, Aşan Mehmet Ali, Bozdağ Ahmet, Bahçecioğlu İbrahim Halil, Akbulut Ayhan, Demirdağ Kutbeddin
Fırat University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Elazığ, Türkiye.
Fırat University Faculty of Medicine, Department of General Surgery, Elazığ, Türkiye.
Turkiye Parazitol Derg. 2025 Jul 18;49(2):58-62. doi: 10.4274/tpd.galenos.2025.42650.
Fascioliasis is a trematode infection caused by or . Diagnosis of fascioliasis is often delayed. This study aims to contribute to reducing the incidence of the disease by determining regional epidemiology and guiding public health measures, as well as increasing awareness among physicians through the examination of clinical, laboratory, and imaging findings.
Patients diagnosed with fascioliasis at the Infectious Diseases Clinic and Gastroenterology Clinic of Fırat University Hospital between 2011 and 2022 were included in the study. Demographic information, clinical findings, complete blood count, biochemical parameters, radiological imaging reports, treatment, and prognosis were examined. Patient data were obtained from the hospital automation system, files, and epicrisis.
Of the 19 patients followed, 15 (78.9%) were female. The mean age was 62.36±12.30 years. Fifteen patients (78.9%) lived in rural areas. Seven patients (36.8%) were involved in animal husbandry. Twelve patients (63.2%) had a history of consuming watercress. The most commonly observed symptoms were loss of appetite, right upper quadrant pain, nausea-vomiting, and night sweats. All patients were treated with triclabendazole without any side effects. Statistically significant differences were found in the levels of eosinophilia, alanine transaminase, gamma-glutamyl transferase, alkaline phosphatase, total bilirubin, and direct bilirubin between the beginning of treatment and 1 month in our patients (p<0.05). One patient was lost due to intervening cardiac problems.
Fascioliasis is also present in our region, and a significant history of watercress consumption is noteworthy epidemiologically. should be considered in patients presenting with abdominal pain accompanied by peripheral eosinophilia. Increasing awareness among physicians will contribute to preventing delays in diagnosis and treatment.
肝片吸虫病是由 或 引起的吸虫感染。肝片吸虫病的诊断常常延迟。本研究旨在通过确定区域流行病学并指导公共卫生措施来降低该病的发病率，以及通过检查临床、实验室和影像学检查结果来提高医生的认识。
纳入2011年至2022年期间在菲拉特大学医院传染病科和胃肠病科被诊断为肝片吸虫病的患者。检查人口统计学信息、临床检查结果、全血细胞计数、生化参数、放射影像学报告、治疗情况和预后。患者数据从医院自动化系统、病历和病情记录中获取。
在随访的19例患者中，15例（78.9%）为女性。平均年龄为62.36±12.30岁。15例患者（78.9%）生活在农村地区。7例患者（36.8%）从事畜牧业。12例患者（63.2%）有食用水田芥的病史。最常观察到的症状是食欲不振、右上腹疼痛、恶心呕吐和盗汗。所有患者均接受三氯苯达唑治疗，无任何副作用。在我们的患者中，治疗开始时与治疗1个月时相比，嗜酸性粒细胞增多、丙氨酸转氨酶、γ-谷氨酰转移酶（γ-GT）、碱性磷酸酶、总胆红素和直接胆红素水平存在统计学显著差异（p<0.05）。1例患者因并发心脏问题失访。
我们所在地区也存在肝片吸虫病，从流行病学角度来看，食用水田芥的显著病史值得关注。对于出现腹痛并伴有外周嗜酸性粒细胞增多的患者应考虑该病。提高医生的认识将有助于防止诊断和治疗的延迟。
