Bryukhin G V, Laskov D S, Gribachyova N V, Solyannikova D R
South-Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia.
Bull Exp Biol Med. 2025 Jul 18. doi: 10.1007/s10517-025-06423-w.
We studied the effect of bisphenol A orally administrated to female rats on sexual behavior of their offspring. The males of the experimental group demonstrated significantly decreased number of approaches to a partition separating them from a receptive female; the copulatory rate during direct interaction with the female was also reduced. In females of the experimental group, the lordosis quotient and lordosis intensity were decreased. The revealed changes indicate that bisphenol A intoxication of female rats leads to significant disturbance of sexual behavior in their offspring of both sexes.
我们研究了对雌性大鼠口服双酚A对其后代性行为的影响。实验组的雄性大鼠表现出接近分隔它们与处于接受状态雌性大鼠的隔板的次数显著减少；与雌性大鼠直接互动期间的交配率也降低了。实验组的雌性大鼠，其脊柱前凸商和脊柱前凸强度均降低。所发现的这些变化表明，雌性大鼠双酚A中毒会导致其两性后代的性行为出现显著紊乱。
