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内分泌干扰性食品化学污染物的来源、膳食暴露及毒性:综述

Origin, dietary exposure, and toxicity of endocrine-disrupting food chemical contaminants: A comprehensive review.

作者信息

Peivasteh-Roudsari Leila, Barzegar-Bafrouei Raziyeh, Sharifi Kurush Aghbolagh, Azimisalim Shamimeh, Karami Marziyeh, Abedinzadeh Solmaz, Asadinezhad Shabnam, Tajdar-Oranj Behrouz, Mahdavi Vahideh, Alizadeh Adel Mirza, Sadighara Parisa, Ferrante Margherita, Conti Gea Oliveri, Aliyeva Aynura, Mousavi Khaneghah Amin

机构信息

Food and Drug Administration of Iran, Ministry of Health and Medical Education, Tehran, Iran.

Department of Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

出版信息

Heliyon. 2023 Jul 11;9(7):e18140. doi: 10.1016/j.heliyon.2023.e18140. eCollection 2023 Jul.

Abstract

Endocrine-disrupting chemicals (EDCs) are a growing public health concern worldwide. Consumption of foodstuffs is currently thought to be one of the principal exposure routes to EDCs. However, alternative ways of human exposure are through inhalation of chemicals and dermal contact. These compounds in food products such as canned food, bottled water, dairy products, fish, meat, egg, and vegetables are a ubiquitous concern to the general population. Therefore, understanding EDCs' properties, such as origin, exposure, toxicological impact, and legal aspects are vital to control their release to the environment and food. The present paper provides an overview of the EDCs and their possible disrupting impact on the endocrine system and other organs.

摘要

内分泌干扰化学物质(EDCs)是全球范围内日益受到关注的公共卫生问题。目前认为,食品消费是接触EDCs的主要途径之一。然而,人类接触EDCs的其他途径包括吸入化学物质和皮肤接触。食品中的这些化合物,如罐头食品、瓶装水、乳制品、鱼类、肉类、蛋类和蔬菜,是普通民众普遍关注的问题。因此,了解EDCs的性质,如来源、接触途径、毒理学影响和法律方面,对于控制它们向环境和食品中的释放至关重要。本文概述了EDCs及其对内分泌系统和其他器官可能产生的干扰影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3131/10395372/526d2c9ed4c8/gr1.jpg

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