液体制剂中的局部止血和伤口愈合剂。
Local Hemostatic and Wound-Healing Agent in a Liquid Dosage Form.
作者信息
Khonina T G, Alekseenko S G, Dobrinskaya M N, Izmozherova N V, Larionov L P, Tishin D S, Shadrina E V, Frolova V M, Zamyatin A V, Chupakhin O N
机构信息
I. Ya. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia.
Ural State Agrarian University, Ekaterinburg, Russia.
出版信息
Bull Exp Biol Med. 2025 Jul 18. doi: 10.1007/s10517-025-06428-5.
We propose a composition of a local hemostatic and wound-healing agent in a liquid dosage form, a water-glycerol colloidal suspension containing active substances (silicon and iron glycerolates and chitosan) and an auxiliary substance polyvinylpyrrolidone. The agent is nontoxic and exhibits high hemostatic activity (that was practically the same at different contents of iron (III) monoglycerolate (0.40 and 0.80 wt%)) and pronounced wound-healing properties.
我们提出一种液体剂型的局部止血和伤口愈合剂组合物，一种含有活性物质（甘油硅酸和铁以及壳聚糖）和辅助物质聚乙烯吡咯烷酮的水 - 甘油胶体悬浮液。该制剂无毒，具有高止血活性（在不同含量的甘油单油酸铁（III）（0.40和0.80 wt%）下实际上相同）以及显著的伤口愈合特性。
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