Suppr超能文献

肥胖低通气综合征与道路交通事故风险

Obesity hypoventilation syndrome and risk of road traffic accidents.

作者信息

Ozduygu Gulfem, Kiyan Esen, Pihtili Aylin, Arslan Felemez, Bingol Zuleyha, Okumus Gulfer

机构信息

Istanbul Faculty of Medicine, Department of Pulmonary Medicine, Istanbul University, Fatih, Istanbul, 34360, Türkiye.

University of Health Sciences, Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, 34147, Türkiye.

出版信息

Sleep Breath. 2025 Jul 18;29(4):247. doi: 10.1007/s11325-025-03378-0.

Abstract

PURPOSE

The relationship between obesity hypoventilation syndrome (OHS) and traffic accidents has not been previously studied. We aimed to determine the frequency of traffic accidents and the associated risk factors among people with OHS and compare with obstructive sleep apnoea (OSA) individuals.

METHODS

We screened patients diagnosed with OSA and/or OHS in our sleep laboratory between 2015 and 2023. Patients who had a driver's license, had been driving for at least five years, at least three days a week, and drove more than 5000 km/year and had not received positive airway pressure treatment prior to their diagnosis were included. Polysomnographic data, the Epworth Sleepiness Scale (ESS), the Berlin Sleep Questionnaire were collected from the records. The Fatigue Assessment Scale (FAS) and inattention scores before the diagnosis, driving information and accident numbers from the three years before the diagnosis to the phone call were evaluated.

RESULTS

A total of 121 patients (OHS/OSA: 43/78, F/M: 5/116, age: 46.9 ± 9.7 years, body mass index [BMI]: 32.5 ± 5.7 kg/m²) were included. ESS, FAS, apnoea-hypopnea index (AHI), oxygen desaturation index (ODI) and percentage of total sleep time with SpO less than 90% were significantly greater in OHS patients (p = 0.012, p = 0.028, p = 0.003, p = 0.002 and p = 0.021, respectively). The frequency of accidents was greater in OHS patients than in OSA patients (46.5% vs. 26.9%, p = 0.029). In the multivariate analysis, only BMI was an independent factor (OR: 1.185, 95% CI: 1.005-1.396, p = 0.044).

CONCLUSION

Traffic accidents were more common in OHS patients than in OSA patients, with obesity as the primary independent risk factor.

摘要

目的

肥胖低通气综合征(OHS)与交通事故之间的关系此前尚未得到研究。我们旨在确定OHS患者中交通事故的发生率及相关危险因素,并与阻塞性睡眠呼吸暂停(OSA)患者进行比较。

方法

我们对2015年至2023年间在我们睡眠实验室被诊断为OSA和/或OHS的患者进行了筛查。纳入的患者需持有驾驶执照,至少已驾驶五年,每周至少驾驶三天,每年驾驶里程超过5000公里,且在诊断前未接受过气道正压治疗。从记录中收集多导睡眠图数据、爱泼华嗜睡量表(ESS)、柏林睡眠问卷。评估诊断前的疲劳评估量表(FAS)和注意力不集中得分、驾驶信息以及从诊断前三年到电话随访时的事故数量。

结果

共纳入121例患者(OHS/OSA:43/78,男/女:5/116,年龄:46.9±9.7岁,体重指数[BMI]:32.5±5.7kg/m²)。OHS患者的ESS、FAS、呼吸暂停低通气指数(AHI)、氧饱和度下降指数(ODI)以及睡眠期间SpO₂低于90%的总睡眠时间百分比均显著更高(分别为p = 0.012、p = 0.028、p = 0.003、p = 0.002和p = 0.021)。OHS患者的事故发生率高于OSA患者(46.5%对26.9%,p = 0.029)。在多变量分析中,只有BMI是独立因素(比值比:1.185,95%置信区间:1.005 - 1.396,p = 0.044)。

结论

OHS患者比OSA患者更容易发生交通事故,肥胖是主要的独立危险因素。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验