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超声引导下微波消融治疗儿童自主性高功能甲状腺结节

Ultrasound-Guided Microwave Ablation for Autonomous Hyperfunctioning Thyroid Nodule in a Child.

作者信息

Li Meiye, Li Xin, Zhang Hongxia, Chen Jingyu, Zhao Zhenzhen, Zhang Jun, Kong Xiangru

机构信息

Department of Endocrinology, The 960th Hospital of PLA Joint Logistics Support Force, Jinan, 250014, China.

Department of Oncological Surgery, Children's Hospital of Chongqing Medical University, Chongqing, 400014, China.

出版信息

Indian J Pediatr. 2025 Jul 18. doi: 10.1007/s12098-025-05678-5.

DOI:10.1007/s12098-025-05678-5
PMID:40679741
Abstract

Microwave ablation (MWA) can be used to treat autonomously functioning thyroid nodules. The authors performed ultrasound-guided microwave ablation on a child with an autonomously functioning thyroid nodule who was unwilling to undergo surgery. The patient was a 12-y-old girl with anxiety, weakness, tremors, palpitations, heat intolerance and weight loss. Since I treatment is unsuitable for pediatric patients, ultrasound-guided microwave ablation was performed. Postoperatively, her symptoms improved and she gained weight. Thyroid hormone levels normalized within a month, and the neck mass shrank. Follow-up at 9 mo showed the nodule gradually shrinking. Microwave ablation is a safe and effective treatment for pediatric autonomously functioning thyroid nodules. Future studies are needed to assess long-term outcomes.

摘要

微波消融(MWA)可用于治疗自主功能性甲状腺结节。作者对一名不愿接受手术的自主功能性甲状腺结节患儿进行了超声引导下的微波消融。患者为一名12岁女孩,有焦虑、乏力、震颤、心悸、不耐热和体重减轻等症状。由于碘治疗不适用于儿科患者,因此进行了超声引导下的微波消融。术后,她的症状有所改善,体重增加。甲状腺激素水平在一个月内恢复正常,颈部肿块缩小。9个月的随访显示结节逐渐缩小。微波消融是治疗儿科自主功能性甲状腺结节的一种安全有效的方法。需要进一步的研究来评估长期疗效。

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本文引用的文献

1
Role of Thyroid RFA in the Treatment of Autonomously Functioning Thyroid Nodules.甲状腺射频消融术在自主性功能性甲状腺结节治疗中的作用
Tech Vasc Interv Radiol. 2022 Jun;25(2):100823. doi: 10.1016/j.tvir.2022.100823. Epub 2022 Mar 12.
2
Radiofrequency Ablation and Autonomous Functioning Thyroid Nodules: Review of the Current Literature.射频消融与自主性甲状腺结节:当前文献综述
Laryngoscope. 2022 Apr;132(4):906-914. doi: 10.1002/lary.29811. Epub 2021 Aug 10.
3
Safety and Efficacy of Radiofrequency Ablation of Thyroid Nodules-Expanding Treatment Options in the United States.
甲状腺结节射频消融的安全性与有效性——美国不断拓展的治疗选择
J Endocr Soc. 2021 Jun 10;5(8):bvab110. doi: 10.1210/jendso/bvab110. eCollection 2021 Aug 1.
4
Ultrasound-guided radiofrequency ablation (RFA) of benign symptomatic thyroid nodules - initial UK experience.超声引导下对有症状的良性甲状腺结节进行射频消融术——英国的初步经验。
Br J Radiol. 2019 Jun;92(1098):20190026. doi: 10.1259/bjr.20190026. Epub 2019 May 14.
5
Rapid Relief: Thyroidectomy is a Quicker Cure than Radioactive Iodine Ablation (RAI) in Patients with Hyperthyroidism.快速缓解:对于甲亢患者,甲状腺切除术比放射性碘消融(RAI)能更快治愈。
World J Surg. 2019 Mar;43(3):812-817. doi: 10.1007/s00268-018-4864-7.