Ni Shuang, Wang Jingwen, Lyu Danni, Xu Zhe, Xu Jing-Wei, Zhu Sha, Feng Yixuan, Shi Ce, Xu Wen
Eye Center, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, People's Republic of China.
Zhejiang Provincial Key Lab of Ophthalmology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, People's Republic of China.
Sci Rep. 2025 Jul 18;15(1):26095. doi: 10.1038/s41598-025-11332-z.
This study aimed to evaluate the accuracy of six intraocular lens (IOL) calculation formulas using total keratometry (TK) and standard keratometry (K) measurements from the IOLMaster 700 in various ocular subgroups. A total of 212 eyes were analyzed. The mean absolute error (MAE), standard deviation (SD) of prediction error, and the median absolute error (MedAE) were calculated for each formula. and the prediction accuracy was compared across different subgroups categorized by axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and other ocular parameters. Results showed that the Barrett Universal II (BU II) formula consistently had the lowest MAEs and MedAEs in the overall sample and most subgroups. The BU II formula performed particularly well in subgroups with thin LT when using TK mode and in medium LT subgroups using K mode. Comparison between TK and K modes showed no consistent superiority, with each mode outperforming the other in specific subgroups. The accuracy of the BU II formula was not influenced by ocular parameters, suggesting its robustness across different patient groups. In conclusion, the BU II formula demonstrated superior accuracy compared to other formulas, especially in specific subgroups, and its performance remained consistent regardless of ocular measurement variations.
本研究旨在使用IOLMaster 700的全角膜曲率计（TK）和标准角膜曲率计（K）测量值，评估六种人工晶状体（IOL）计算公式在不同眼部亚组中的准确性。共分析了212只眼。计算每个公式的平均绝对误差（MAE）、预测误差的标准差（SD）和中位数绝对误差（MedAE），并比较按眼轴长度（AL）、前房深度（ACD）、晶状体厚度（LT）和其他眼部参数分类的不同亚组的预测准确性。结果显示，在总体样本和大多数亚组中，Barrett通用II（BU II）公式的MAE和MedAE始终最低。当使用TK模式时，BU II公式在LT薄的亚组中表现特别好，而在使用K模式的中等LT亚组中表现也很好。TK和K模式之间的比较没有显示出一致的优越性，每种模式在特定亚组中都优于另一种模式。BU II公式的准确性不受眼部参数的影响，表明其在不同患者群体中的稳健性。总之，与其他公式相比，BU II公式显示出更高的准确性，尤其是在特定亚组中，并且无论眼部测量变化如何，其性能都保持一致。
