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急诊科收治的上消化道出血患者中,新风险评分(ABL)与格拉斯哥布莱奇福德评分、AIMS65评分及内镜前罗卡尔评分的比较。

Comparison of the new risk score (ABL) with the Glasgow Blatchford Score, AIMS65, and pre-endoscopic Rockall Score in patients with upper gastrointestinal bleeding admitted to the emergency department.

作者信息

Güner Necip Gökhan, Çatal Fatih, Yürümez Yusuf, Güneysu Fatih, Bostancı Furkan

机构信息

Department of Emergency Medicine, Sakarya University School of Medicine, Sakarya, Turkey.

Department of Emergency Medicine, Siirt Training and Research Hospital, Siirt, Turkey.

出版信息

BMC Emerg Med. 2025 Jul 18;25(1):131. doi: 10.1186/s12873-025-01291-z.

Abstract

BACKGROUND

Upper gastrointestinal bleeding (UGIB) continues to be a major global health concern, contributing substantially to both morbidity and mortality. This highlights the need for efficient and reliable risk assessment methods, particularly in emergency care settings. The primary objective of this study was to create a new risk scoring system that is easier to apply, more practical in clinical workflows, and highly effective for evaluating patients presenting to the emergency department with UGIB.

METHODS

This retrospective observational study was conducted at a single center by analyzing records of patients aged 18 years and older who presented to the Emergency Medicine Department of Sakarya Training and Research Hospital with clinical signs and symptoms suggestive of upper gastrointestinal bleeding (UGIB) between January 2022 and June 2023. For analytical purposes, patients were categorized into six distinct subgroups. Those assigned to transfusion, intervention, intensive care unit (ICU), readmission, or mortality groups were collectively defined as high-risk patients. Based on the collected clinical data, a novel scoring system-referred to as the ABL score-was developed. The diagnostic performance of this new score in identifying high-risk patients and each outcome subgroup was then evaluated and compared to existing scoring tools: the Glasgow Blatchford Score (GBS), AIMS65, and the pre-endoscopic Rockall Score (Pre-RS).

RESULTS

A total of 589 patients were included, with a median age of 67 years, with a male ratio of 66.2%. ABL score, which includes Age, systolic Blood pressure, Laboratory parameters (hemoglobin, BUN/creatinine ratio, and international normalized ratio/albümin) was found to be more effective in predicting high-risk groups compared to the GBS, AIMS65, and Pre-RS scores ([AUROC]: 0.86, 0.806, 0.71, and 0.704, respectively; p < 0.05). The ABL score also performed better in predicting transfusion and readmission subgroups. (AUROC: 0.886 and 0.719, respectively).

CONCLUSION

The ABL scoring system demonstrated higher predictive performance than GBS, AIMS65, and Pre-RS, particularly in identifying high-risk patients, transfusion requirements, and the likelihood of readmission. However, confirmation of these findings requires validation through larger, prospective studies.

摘要

背景

上消化道出血(UGIB)仍然是一个重大的全球健康问题,对发病率和死亡率都有很大影响。这凸显了高效可靠的风险评估方法的必要性,尤其是在急诊护理环境中。本研究的主要目的是创建一种新的风险评分系统,该系统更易于应用,在临床工作流程中更实用,并且对于评估因UGIB就诊于急诊科的患者非常有效。

方法

本回顾性观察性研究在一个单一中心进行,通过分析2022年1月至2023年6月期间因临床症状和体征提示上消化道出血(UGIB)而就诊于萨卡里亚培训与研究医院急诊科的18岁及以上患者的记录。为了进行分析,将患者分为六个不同的亚组。那些被分配到输血、干预、重症监护病房(ICU)、再次入院或死亡组的患者被统称为高危患者。基于收集到的临床数据,开发了一种新的评分系统——称为ABL评分。然后评估了这个新评分在识别高危患者和每个结局亚组方面的诊断性能,并与现有的评分工具进行比较:格拉斯哥布莱奇福德评分(GBS)、AIMS65和内镜前罗卡尔评分(Pre-RS)。

结果

共纳入589例患者,中位年龄为67岁,男性比例为66.2%。发现包括年龄、收缩压、实验室参数(血红蛋白、尿素氮/肌酐比值和国际标准化比值/白蛋白)的ABL评分在预测高危组方面比GBS、AIMS65和Pre-RS评分更有效([曲线下面积]:分别为0.86、0.806、0.71和0.704;p<0.05)。ABL评分在预测输血和再次入院亚组方面也表现更好。(曲线下面积:分别为0.886和0.719)。

结论

ABL评分系统显示出比GBS、AIMS65和Pre-RS更高的预测性能,特别是在识别高危患者、输血需求和再次入院可能性方面。然而,这些发现需要通过更大规模的前瞻性研究进行验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43ef/12275245/eced0a4f662c/12873_2025_1291_Fig1_HTML.jpg

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