Krešo Ante, Batistić Darko, Vrdoljak Josip, Znaor Ljubo, Marušić Ana
Department of Ophthalmology, University Hospital of Split, Spinčićeva 1, 21000, Split, Croatia.
Department of Pathophysiology, School of Medicine, University of Split, Split, Croatia.
Int Ophthalmol. 2025 Jul 19;45(1):299. doi: 10.1007/s10792-025-03659-3.
This study aimed to evaluate the knowledge, attitudes, and experiences of glaucoma patients about the side effects of intraocular pressure (IOP)-lowering medications in glaucoma, focusing on how these factors affect treatment adherence.
We conducted a cross-sectional survey during routine visits to glaucoma clinic, with participants aged 18 years or older on IOP-lowering medications for at least 6 months. The survey, consisting of 22 questions about various aspects of IOP-lowering medications and side effects.
Most out of 398 analysed patients were not informed about side effects when IOP-lowering medication was prescribed, and 68.1% reported experiencing side effects. A significant number of participants reported changing IOP-lowering medications due to side effects. Higher self-reported knowledge about side effects was associated with lower concern (coef. = - 0.1636, P = 0.048) about side effects.
The study identified significant gaps in patient education and support about IOP-lowering medications side effects. Better communication and education by healthcare providers could improve treatment adherence, consequentially enhancing clinical outcomes and quality of life for glaucoma patients.
本研究旨在评估青光眼患者对降低眼压药物副作用的知晓情况、态度及经历，重点关注这些因素如何影响治疗依从性。
我们在青光眼门诊的常规就诊期间进行了一项横断面调查，参与者为年龄在18岁及以上且使用降低眼压药物至少6个月的患者。该调查由22个关于降低眼压药物及副作用各方面的问题组成。
在398名接受分析的患者中，大多数在开具降低眼压药物处方时未被告知副作用，68.1%的患者报告有副作用经历。相当数量的参与者报告因副作用而更换降低眼压药物。自我报告的关于副作用的知识水平较高与对副作用的担忧较低相关（系数= -0.1636，P = 0.048）。
该研究发现患者在关于降低眼压药物副作用的教育和支持方面存在显著差距。医疗服务提供者更好地沟通和教育可以提高治疗依从性，从而改善青光眼患者的临床结局和生活质量。
