Zhong Wenyan, Chen Zailiang, Shen Hailan, Liu Xinyi, Xiong Wanqing, Lui Hui
School of Computer Science, Central South University, No. 932, Lushan South Road, Changsha, 410083, Hunan Province, China.
Xiangya Hospital, Central South University, No. 85 Xiangya Road, Kaifu District, Changsha, 410000, Hunan Province, China.
Comput Med Imaging Graph. 2025 Sep;124:102603. doi: 10.1016/j.compmedimag.2025.102603. Epub 2025 Jul 16.
Automated segmentation of Magnetic Resonance (MR) images plays a critical role in medical applications, including tumor delineation, organ volume measurement, and lesion tracking. While traditional supervised learning methods depend heavily on costly annotated data, MR images inherently contain rich anatomical information, such as the shape, size, and spatial relationships of organs and tissues. Effectively leveraging this information to enhance segmentation performance remains a significant challenge in current research. To address this, we propose a novel Dual-task Feature Mining Framework (DFMF), which integrates self-supervised and semi-supervised learning paradigms. DFMF simultaneously optimizes two complementary tasks: image inpainting and segmentation, enabling the extraction of richer and more discriminative feature representations. This dual-task mechanism enhances the model's ability to capture complex anatomical structures, leading to superior segmentation performance. To maximize the utility of unannotated data, we introduce a Self-consistency Loss, which enforces consistency between inpainted and original images without requiring explicit data augmentation. Additionally, we design a Hybrid Receptive Field Network (HRFNet) as the backbone of DFMF, which effectively captures global frequency-domain information while preserving fine spatial details. Extensive experiments on four MR image datasets demonstrate that DFMF outperforms state-of-the-art segmentation methods, and ablation studies validate the contribution of each component from multiple perspectives.
磁共振(MR)图像的自动分割在医学应用中起着关键作用,包括肿瘤轮廓描绘、器官体积测量和病变跟踪。虽然传统的监督学习方法严重依赖于昂贵的标注数据,但MR图像本身包含丰富的解剖学信息,如器官和组织的形状、大小及空间关系。在当前研究中,有效利用这些信息来提高分割性能仍然是一项重大挑战。为解决这一问题,我们提出了一种新颖的双任务特征挖掘框架(DFMF),它整合了自监督和半监督学习范式。DFMF同时优化两个互补任务:图像修复和分割,从而能够提取更丰富、更具判别力的特征表示。这种双任务机制增强了模型捕捉复杂解剖结构的能力,进而带来卓越的分割性能。为了最大化未标注数据的效用,我们引入了一种自一致性损失,它无需显式的数据增强即可强制修复图像与原始图像之间的一致性。此外,我们设计了一种混合感受野网络(HRFNet)作为DFMF的主干,它在保留精细空间细节的同时有效地捕捉全局频域信息。在四个MR图像数据集上进行的大量实验表明,DFMF优于当前最先进的分割方法,并且消融研究从多个角度验证了每个组件的贡献。