Shin Min-Hye, Lee Young-Jae, Park Kyung Eun, Kim Yeonhee, Won Ha-Kyeong, Ahn Kyung-Min, Shim Ji-Su, Kim Min-Hye, An Jin, Jeong Jiung, Kim Young-Chan, Lee Hwa Young, Kang Sung-Yoon, Park Han-Ki, Jo Eun-Jung, Lee Seung-Eun, Kim So Ri, Chang Yoon-Seok, Lee Byung-Jae, Morice Alyn H, Song Woo-Jung
Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43-gil, Songpa-gu, Seoul, 05505, Korea.
University of Ulsan College of Medicine, Seoul, Korea.
Lung. 2025 Jul 20;203(1):81. doi: 10.1007/s00408-025-00836-0.
The International Classification of Diseases (ICD) system plays a key role in health data classification but currently lacks a specific code for refractory chronic cough (RCC). This study analyzed ICD-10 coding patterns among 331 RCC patients enrolled in the Korean Chronic Cough Registry. Each patient had a median of 3 [IQR: 2-4] ICD-10 codes at their most recent outpatient visit. The most frequently assigned primary code was R05 (Cough), recorded in 80.4% of cases. Patients with R05 as their primary code tended to have fewer identifiable etiologies but reported more cough hypersensitivity symptoms. Additionally, the number of ICD-10 codes correlated with both cough severity and cough-specific quality-of-life impairment. In a pooled analysis including RCC and non-RCC cases, the R05 code showed high specificity (80.5%) but low sensitivity (25.8%) for RCC. These findings support the need for a dedicated ICD code to accurately capture RCC in clinical and epidemiological contexts.
国际疾病分类（ICD）系统在健康数据分类中起着关键作用，但目前缺乏针对难治性慢性咳嗽（RCC）的特定编码。本研究分析了韩国慢性咳嗽登记处登记的331例RCC患者的ICD - 10编码模式。每位患者在最近一次门诊就诊时的ICD - 10编码中位数为3个[四分位间距：2 - 4个]。最常分配的主要编码是R05（咳嗽），80.4%的病例记录为此编码。以R05作为主要编码的患者往往可识别病因较少，但报告的咳嗽超敏症状较多。此外，ICD - 10编码数量与咳嗽严重程度和咳嗽特异性生活质量损害均相关。在一项包括RCC和非RCC病例的汇总分析中，R05编码对RCC显示出高特异性（80.5%）但低敏感性（25.8%）。这些发现支持需要一个专门的ICD编码，以便在临床和流行病学背景下准确识别RCC。
