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降低亚洲印度移民心血管疾病风险因素的干预措施:一项范围综述方案

Interventions to lower cardiovascular disease risk factors among Asian Indian immigrants: a scoping review protocol.

作者信息

Mobarki Abeer M, D'Alonzo Karen T, Joseph Maya E, Wadhawan Anju, Mathur Shailja, Holly Cheryl

机构信息

School of Nursing, Rutgers The State University of New Jersey, Newark, New Jersey, USA.

School of Nursing, Rutgers The State University of New Jersey, Newark, New Jersey, USA

出版信息

BMJ Open. 2025 Jul 20;15(7):e100339. doi: 10.1136/bmjopen-2025-100339.

Abstract

INTRODUCTION

To identify effective interventions to lower cardiovascular disease (CVD) risk factors among Asian Indian (AI) immigrants.As the second largest immigrant group in the USA, AI immigrants experience CVD prevalence rates as high as 13% among males and 4.4% among females; these rates are significantly higher than other Asian subgroups and the general US population. Despite extensive knowledge of CVD risk factors, there have been few cardioprotective interventions in this population.

METHODS AND ANALYSIS

Interventional studies of first-generation AI immigrants aged 18-70 years, conducted between 2000 and 2025, will be identified, including randomised controlled trials, factorial and cross-over designs, and cluster randomised trials. We will include AIs with and without a specific family history of CVD, or personal history of type 2 diabetes mellitus, hyperlipidaemia or obesity. Exclusion criteria include AIs born in the USA or visiting.The Arksey and O'Malley methodology framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews will be used for analysis. A preliminary review of interventions to lower the CVD risk in AIs will guide the research questions (stage 1). Relevant articles published between 2000 and 2025 will be retrieved using electronic databases and search terms (stage 2). Two independent reviewers will select studies based on eligibility criteria (stage 3). Reviewers will determine eligibility status, screen full texts and retrieve relevant publications. Reviewers will extract data, capturing study design, sample characteristics, types of interventions, outcomes and key findings (stage 4). A summary of results will be presented (stage 5). The review will identify the most effective interventions, potential areas for future research and practical recommendations to improve CVD outcomes among AI immigrants.

ETHICS AND DISSEMINATION

Included studies will meet ethical standards in research. Findings will be disseminated through manuscripts, presentations at relevant conferences and community outreach programmes to promote effective interventions.

摘要

引言

确定有效干预措施以降低亚裔印度移民的心血管疾病(CVD)风险因素。作为美国第二大移民群体,亚裔印度移民的心血管疾病患病率在男性中高达13%,在女性中为4.4%;这些患病率显著高于其他亚洲亚组和美国普通人群。尽管对心血管疾病风险因素有广泛了解,但针对该人群的心脏保护干预措施却很少。

方法与分析

将确定2000年至2025年间对18至70岁的第一代亚裔印度移民进行的干预性研究,包括随机对照试验、析因设计和交叉设计以及整群随机试验。我们将纳入有或没有心血管疾病特定家族史、或2型糖尿病、高脂血症或肥胖个人史的亚裔印度人。排除标准包括在美国出生或来访的亚裔印度人。将使用阿克斯赛和奥马利方法框架以及系统评价和元分析扩展版的首选报告项目进行范围综述分析。对降低亚裔印度人心血管疾病风险的干预措施进行初步综述将指导研究问题(第1阶段)。将使用电子数据库和检索词检索2000年至2025年间发表的相关文章(第2阶段)。两名独立评审员将根据纳入标准选择研究(第3阶段)。评审员将确定纳入状态、筛选全文并检索相关出版物。评审员将提取数据,记录研究设计、样本特征、干预类型、结果和主要发现(第4阶段)。将呈现结果总结(第5阶段)。该综述将确定最有效的干预措施、未来研究的潜在领域以及改善亚裔印度移民心血管疾病结局的实用建议。

伦理与传播

纳入的研究将符合研究伦理标准。研究结果将通过手稿、在相关会议上的报告以及社区外展项目进行传播,以推广有效的干预措施。

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