Klein S, Zenker H J
Klin Monbl Augenheilkd. 1985 Sep;187(3):184-6. doi: 10.1055/s-2008-1051013.
Fluorescein angiographies of the iris and retina were performed both in normal individuals (104) and in patients suffering from hyperlipoproteinemia (48), maturity-onset diabetes (184), systemic hypertension (12) and atherosclerosis (12). While hyperpermeation of dye located at the pupillary border was seen in 7.7% of the normals, leakages occurred in 66.6% of the hyperlipoproteinemics and in 79% of the recent maturity-onset diabetics. Paraclinical examination of the normal subjects with pathologic dye transit revealed vascular risk factors in each case. Thus, fluorescein iris angiography is a suitable method of detecting vascular damage in cases of metabolic disorder as early as possible.
对104名正常个体以及48名患有高脂蛋白血症、184名成年型糖尿病、12名系统性高血压和12名动脉粥样硬化的患者进行了虹膜和视网膜荧光血管造影。虽然在7.7%的正常个体中可见位于瞳孔边缘的染料高渗透，但在66.6%的高脂蛋白血症患者和79%的近期成年型糖尿病患者中出现了渗漏。对染料传输异常的正常受试者进行的临床旁检查在每种情况下均发现了血管危险因素。因此，荧光素虹膜血管造影是尽早检测代谢紊乱病例中血管损伤的合适方法。
