Mohammed Salhadin, Bime Aman Edao, Sedi China Tolessa, Saliha Hussen Nuri, Maru Surafel Tilahun, Mustafa Abdulfatah Workicho
Internal Medicine Department, Division of Neurology, School of Medicine, College of Health Sciences, Wollo University, Dessie, Ethiopia.
Anaesthesiology, Critical Care, and Pain Medicine Department, School of Medicine, College of Health Sciences, Haramaya University, Harar, Ethiopia.
Radiol Case Rep. 2025 Jul 5;20(9):4820-4824. doi: 10.1016/j.radcr.2025.06.043. eCollection 2025 Sep.
Severe dengue can lead to fatal complications, including dengue encephalitis. We report a 14-year-old girl with severe dengue who presented with bilateral thalamic hemorrhagic infarction, indicated by distinct brain imaging findings (the so-called "double doughnut sign"), which is a rare presentation of a common infection. Positive dengue antigen and IgM tests were noted. The patient required critical care, including intubation and resuscitation, but was discharged improved and continues follow-up at our neurology clinic. This case highlights that dengue infection can be complicated by meningoencephalitis, and a high index of suspicion is needed to diagnose our patients promptly. Furthermore, imaging modalities such as MRI play a key role in diagnosing and managing patients with dengue encephalitis.
严重登革热可导致致命并发症，包括登革热脑炎。我们报告一名14岁患有严重登革热的女孩，其脑部影像学检查发现双侧丘脑出血性梗死（即所谓的“双甜甜圈征”），这是一种常见感染的罕见表现。登革热抗原和IgM检测呈阳性。患者需要重症监护，包括插管和复苏，但出院时情况有所改善，并继续在我们的神经科门诊接受随访。该病例强调登革热感染可并发脑膜脑炎，需要高度怀疑指数才能及时诊断我们的患者。此外，MRI等影像学检查在登革热脑炎患者的诊断和管理中起着关键作用。
