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口服清液对成年手术患者术前缩短禁食时间的安全性及效果:一项随机对照试验

The safety and effect of preoperative reduced fasting time by oral clear liquid administration in adult surgery patients: a randomized controlled trial.

作者信息

Lee Donghyoun, Kim Soo-Jin, Chang Won-Bae

机构信息

Department of Surgery, Jeju National University Hospital, Jeju National University College of Medicine, Jeju, Korea.

Department of Nursing, Jeju National University Hospital, Jeju, Korea.

出版信息

Ann Surg Treat Res. 2025 Jul;109(1):1-6. doi: 10.4174/astr.2025.109.1.1. Epub 2025 Jul 2.

DOI:10.4174/astr.2025.109.1.1
PMID:40688262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12270921/
Abstract

PURPOSE

Traditionally, 6-8 hours of fasting has been recommended before surgery to prevent respiratory complications. However, recent evidence suggests that intake of clear fluids up to 2 hours before general anesthesia may be safe. This study aimed to evaluate the safety and efficacy of reduced fasting time with clear liquid intake in surgical patients under general anesthesia.

METHODS

In this randomized controlled trial, 60 adult patients undergoing elective endoscopic total extraperitoneal plasty under general anesthesia were divided into two groups (n = 30 each). The control group fasted overnight (nothing per oral), while the liquid group was allowed clear fluids until 2 hours before surgery. Gastric content volume and pH were measured after intubation. Thirst and hunger levels were assessed pre- and postoperatively using a visual analogue scale. Postoperative hoarseness, nausea, vomiting, and oxygen saturation were monitored in the recovery room.

RESULTS

The liquid group consumed an average of 520 mL of fluid. No serious respiratory complications were observed in either group. Pre- and postoperative thirst and hunger scores were significantly lower in the liquid group (P < 0.001). Gastric content volume and acidity showed no significant differences between groups, with most patients having negligible volumes (<1 mL).

CONCLUSION

Permitting clear liquid intake up to 2 hours before general anesthesia is safe and does not increase the risk of respiratory complications. It effectively reduces thirst and hunger, improving patient comfort without compromising safety.

摘要

目的

传统上,手术前建议禁食6 - 8小时以预防呼吸并发症。然而,最近的证据表明,全身麻醉前2小时内摄入清亮液体可能是安全的。本研究旨在评估全身麻醉下手术患者缩短禁食时间并摄入清亮液体的安全性和有效性。

方法

在这项随机对照试验中,60例接受全身麻醉下择期内镜全腹膜外修补术的成年患者被分为两组(每组n = 30)。对照组禁食过夜(禁口服任何东西),而液体组在手术前2小时可摄入清亮液体。插管后测量胃内容物容量和pH值。术前和术后使用视觉模拟量表评估口渴和饥饿程度。在恢复室监测术后声音嘶哑、恶心、呕吐和氧饱和度。

结果

液体组平均摄入520毫升液体。两组均未观察到严重的呼吸并发症。液体组术前和术后的口渴和饥饿评分显著更低(P < 0.001)。两组之间胃内容物容量和酸度无显著差异,大多数患者的胃内容物量可忽略不计(<1毫升)。

结论

全身麻醉前2小时允许摄入清亮液体是安全的,且不会增加呼吸并发症的风险。它能有效减轻口渴和饥饿,提高患者舒适度且不影响安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea9/12270921/8a45e4902897/astr-109-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea9/12270921/cd5af753d310/astr-109-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea9/12270921/8a45e4902897/astr-109-1-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea9/12270921/cd5af753d310/astr-109-1-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fea9/12270921/8a45e4902897/astr-109-1-g002.jpg

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