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麻醉中一种罕见但严重并发症的病例报告:硬膜外血补丁后蛛网膜炎。

Case Report of a Rare but Serious Complication in Anesthesia: Arachnoiditis Following an Epidural Blood Patch.

作者信息

Kalpers David, Jean Jérome

机构信息

Anesthesiology, Centre Hospitalier du Luxembourg, Luxembourg, LUX.

出版信息

Cureus. 2025 Jun 18;17(6):e86295. doi: 10.7759/cureus.86295. eCollection 2025 Jun.

DOI:10.7759/cureus.86295
PMID:40688973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12275493/
Abstract

The epidural blood patch (EBP) is an invasive technique used to plug a leak of cerebrospinal fluid, usually following an iatrogenic lesion of the dura mater. This injection of autologous blood into the epidural space is associated with a number of rare but potentially serious complications. We present a case of arachnoiditis in a young parturient who presented with symptoms compatible with intracranial hypotension due to an accidental dural puncture during an obstetric epidural, and who was treated with two epidural blood patches. The diagnosis of arachnoiditis was suspected based on the neurological symptoms and confirmed by magnetic resonance imaging (MRI) of the lumbosacral region. Monitoring after an EBP and potential treatment options for spinal arachnoiditis are a current topic of discussion in anesthesia.

摘要

硬膜外血贴疗法(EBP)是一种侵入性技术,通常在硬脑膜发生医源性损伤后用于封堵脑脊液漏。将自体血注射到硬膜外间隙会引发一些罕见但可能严重的并发症。我们报告一例年轻产妇发生蛛网膜炎的病例,该产妇因产科硬膜外麻醉时意外硬膜穿刺出现与颅内低压相符的症状,并接受了两次硬膜外血贴治疗。根据神经症状怀疑为蛛网膜炎,并经腰骶部磁共振成像(MRI)确诊。硬膜外血贴治疗后的监测及脊髓蛛网膜炎的潜在治疗方案是目前麻醉领域讨论的话题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/12275493/8018a557f0da/cureus-0017-00000086295-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/12275493/8018a557f0da/cureus-0017-00000086295-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e23/12275493/8018a557f0da/cureus-0017-00000086295-i01.jpg

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本文引用的文献

1
Epidural blood patch: A narrative review.硬膜外血贴:一篇叙述性综述。
Anaesth Crit Care Pain Med. 2022 Oct;41(5):101138. doi: 10.1016/j.accpm.2022.101138. Epub 2022 Aug 2.
2
MRI Findings of Arachnoiditis, Revisited. Is Classification Possible?蛛网膜炎的 MRI 表现,再探。是否可以进行分类?
J Magn Reson Imaging. 2021 Sep;54(3):904-909. doi: 10.1002/jmri.27583. Epub 2021 Feb 28.
3
Arachnoiditis, a complication of epidural blood patch for the treatment of low-pressure headache: A case report and systematic review.蛛网膜炎,硬膜外血贴治疗低颅压头痛的一种并发症:病例报告及系统评价
Headache. 2021 Feb;61(2):244-252. doi: 10.1111/head.14076. Epub 2021 Feb 13.
4
Chronic adhesive arachnoiditis after repeat epidural blood patch.重复硬膜外血补丁术后慢性粘连性蛛网膜炎
Int J Obstet Anesth. 2015 Aug;24(3):280-3. doi: 10.1016/j.ijoa.2015.04.005. Epub 2015 Apr 29.
5
Surgical treatment for symptomatic spinal adhesive arachnoiditis.症状性脊柱粘连性蛛网膜炎的外科治疗
Spine (Phila Pa 1976). 1989 Aug;14(8):870-5. doi: 10.1097/00007632-198908000-00018.