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[关于冈比亚锥虫所致0至6岁儿童非洲人类锥虫病的17年研究报告]

[Report on l7 years of studies of human African trypanosomiasis caused by T. gambiense in children 0-6 years of age].

作者信息

Triolo N, Trova P, Fusco C, Le Bras J

出版信息

Med Trop (Mars). 1985 Jul-Sep;45(3):251-7.

PMID:4068971
Abstract

The authors present 227 cases of human African trypanosomiasis in children between 0 and 6 years, which have been observed for 17 years in the hyperendemic area of Fontem, Cameroon. These cases deal with a subject seldom described in medical literature. The authors especially insist on the velocity of both the contamination and involvement of the nervous system, as well as on the difficulty in settling a diagnosis when failing consider the notion of endemic area. On the other hand, they stress the fact that the efficiency of arsenical treatment is not more dangerous for children than for adults. Finally, they confirm the existence of congenital trypanosomiasis, which proves to be as important from the epidemiological point of view than from the strategical means to be used to identify this disease.

摘要

作者介绍了227例0至6岁儿童的人类非洲锥虫病病例,这些病例在喀麦隆丰特姆高度流行地区已观察了17年。这些病例涉及医学文献中很少描述的一个主题。作者特别强调了感染和神经系统受累的速度,以及在未考虑流行地区概念时难以做出诊断的情况。另一方面,他们强调砷剂治疗对儿童的有效性并不比成人更危险这一事实。最后,他们证实了先天性锥虫病的存在,这从流行病学角度和用于识别该疾病的策略手段来看都同样重要。

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