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[Diagnostics and treatment of gout : S3 guideline of the German Society for Rheumatology and Clinical Immunology (DGRh, lead management) and participating professional societies: German Society for Internal Medicine (DGIM), German Society for General Medicine and Family Medicine (DEGAM), German Society for Nephrology (DGfN), German Society for Orthopaedic and Trauma Surgery (DGOU), German Society for Nutritional Medicine (DGEM), German Roentgen Society-Society for Medical Radiology (DRG), German Rheumatism League].

作者信息

Tausche Anne-Kathrin, Schneidereit Thomas, Napierala Hendrik, Reuß-Borst Monika, Klemm Philipp, Clausen Jürgen, Morf Harriet, Truthmann Julia, Karl Ilja, Engel Bettina, Keyßer Gernot, Müller-Ladner Ulf, Kettritz Ralph, Kielstein Jan, Makowski Marcus, Booz Christian, Carl Hans-Dieter, Gaulke Ralph, Adam Olaf, Michalsen Andreas, Fritsch Michaela, Alten Rieke, Manger Bernhard, Krüger Klaus, Schmidt Wolfgang A, Schwarting Andreas, Braun Jürgen, Kiltz Uta

机构信息

Medizinische Klinik III, Abteilung für Rheumatologie, Universitätsklinikum Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Deutschland.

Fachklinik 360°, Ratingen, Deutschland.

出版信息

Z Rheumatol. 2025 Jul 21. doi: 10.1007/s00393-025-01634-y.

DOI:10.1007/s00393-025-01634-y
PMID:40689975
Abstract
摘要

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本文引用的文献

1
Serum level of IFN-λ is elevated in idiopathic inflammatory myopathies.特发性炎症性肌病患者血清中干扰素-λ水平升高。
Clin Rheumatol. 2025 Jan;44(1):327-340. doi: 10.1007/s10067-024-07227-5. Epub 2024 Nov 23.
2
Novel perspectives on the link between obesity and cancer risk: from mechanisms to clinical implications.肥胖与癌症风险关联的新视角：从机制到临床意义
Front Med. 2024 Dec;18(6):945-968. doi: 10.1007/s11684-024-1094-2. Epub 2024 Nov 14.
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Systematic literature review to inform the EULAR recommendations for the use of imaging in crystal-induced arthropathies in clinical practice.
系统文献综述，为 EULAR 推荐在临床实践中使用影像学检查诊断晶体相关性关节病提供依据。
Ann Rheum Dis. 2024 Aug 27;83(9):1208-1224. doi: 10.1136/ard-2023-225247.
4
Association between serum urate and flares in people with gout and evidence for surrogate status: a secondary analysis of two randomised controlled trials.痛风患者血清尿酸与痛风发作之间的关联及替代指标地位的证据：两项随机对照试验的二次分析
Lancet Rheumatol. 2022 Jan;4(1):e53-e60. doi: 10.1016/S2665-9913(21)00319-2. Epub 2021 Nov 5.
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Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials.贝匹地酸的安全性和疗效：随机对照试验的系统评价和荟萃分析。
Cardiovasc Diabetol. 2023 Nov 28;22(1):324. doi: 10.1186/s12933-023-02022-z.
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In patients with type 2 diabetes or HF, SGLT2 inhibitors reduce gout-related outcomes.在 2 型糖尿病或 HF 患者中，SGLT2 抑制剂可降低痛风相关结局。
Ann Intern Med. 2023 Nov;176(11):JC125. doi: 10.7326/J23-0081. Epub 2023 Nov 7.
7
Sodium glucose cotransporter 2 inhibitors and gout risk: a sequence symmetry analysis.钠-葡萄糖共转运蛋白 2 抑制剂与痛风风险：序列对称分析。
Clin Rheumatol. 2023 Sep;42(9):2469-2475. doi: 10.1007/s10067-023-06647-z. Epub 2023 Jun 2.
8
A randomized pilot trial assessing the reduction of gout episodes in hyperuricemic patients by oral administration of CECT 30632, a strain with the ability to degrade purines.一项随机试点试验，评估口服CECT 30632（一种具有降解嘌呤能力的菌株）对高尿酸血症患者痛风发作次数的减少情况。
Front Microbiol. 2023 Feb 14;14:1111652. doi: 10.3389/fmicb.2023.1111652. eCollection 2023.
9
Association of Dapagliflozin Use With Clinical Outcomes and the Introduction of Uric Acid-Lowering Therapy and Colchicine in Patients With Heart Failure With and Without Gout: A Patient-Level Pooled Meta-analysis of DAPA-HF and DELIVER.达格列净与心力衰竭患者临床结局的相关性以及在伴或不伴痛风患者中降尿酸治疗和秋水仙碱的引入：DAPA-HF 和 DELIVER 的患者水平汇总荟萃分析。
JAMA Cardiol. 2023 Apr 1;8(4):386-393. doi: 10.1001/jamacardio.2022.5608.
10
Feasibility of conducting a randomized, placebo-controlled study assessing whether omega-3 fatty acids prevent gout flares when starting urate-lowering treatment.开展一项随机、安慰剂对照研究的可行性，该研究旨在评估在开始降尿酸治疗时，ω-3脂肪酸是否能预防痛风发作。
Rheumatol Adv Pract. 2022 Oct 25;6(3):rkac086. doi: 10.1093/rap/rkac086. eCollection 2022.