肿瘤神经微环境能否成为重新编程癌症的靶点？
Can the tumor neural niche be targeted to re-program cancer?
作者信息
Sloan Erica K, Lee Joo Sang
机构信息
Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Department of Precision Medicine, School of Medicine and Department of Artificial Intelligence, Sungkyunkwan University, Suwon, Republic of Korea.
出版信息
PLoS Biol. 2025 Jul 21;23(7):e3003266. doi: 10.1371/journal.pbio.3003266. eCollection 2025 Jul.
Abstract
Interactions between the peripheral nervous system and solid tumors influence cancer progression and treatment response. Defining the 3D tumor neural niche using spatial omics and AI technologies will identify new opportunities for targeted therapies to stop cancer progression.
摘要
外周神经系统与实体瘤之间的相互作用会影响癌症进展和治疗反应。利用空间组学和人工智能技术来定义三维肿瘤神经微环境，将为阻止癌症进展的靶向治疗带来新机遇。
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