Gong Fengying, Cheng Yunshui, Li Yongchun, Fan Qin, Qu Rongmei, Fan Tingyu, Lv Ying, Dai Jingxing
Department of Traditional Chinese Medicine, Nanfang Hospital of Southern Medical University, Guangzhou, 510515, People's Republic of China.
The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510405, People's Republic of China.
Cancer Manag Res. 2025 Jul 15;17:1377-1388. doi: 10.2147/CMAR.S529467. eCollection 2025.
Malignant pleural effusion (MPE) is characterized by the accumulation of fluid in the chest cavity, secondary to metastasis from a primary pleural tumor or malignant neoplasms originating from other anatomical sites. MPE is associated with a poor prognosis. Consequently, timely and effective prevention and management of MPE are critical. In Western medicine, the treatment of MPE primarily involves procedures such as surgical puncture for drainage, pleural fixation, chemotherapy, and targeted therapy. In contrast, traditional Chinese medicine (TCM) offers therapeutic modalities including oral decoctions, thoracic perfusion with herbal injections, topical applications of medicinal pastes, and acupoint therapies. The TCM approaches have demonstrated satisfactory clinical outcomes. Advances in the study of TCM for managing MPE in lung tumors are expected to yield a wealth of therapeutic strategies, facilitating the development of more optimized clinical treatments.
恶性胸腔积液（MPE）的特征是胸腔内液体蓄积，继发于原发性胸膜肿瘤的转移或源自其他解剖部位的恶性肿瘤。MPE预后较差。因此，及时有效地预防和处理MPE至关重要。在西医中，MPE的治疗主要包括手术穿刺引流、胸膜固定、化疗和靶向治疗等操作。相比之下，中医提供的治疗方式包括口服汤剂、中药注射剂胸腔灌注、药膏外敷和穴位疗法。中医方法已显示出令人满意的临床效果。预计中医在肺癌MPE管理方面的研究进展将产生丰富的治疗策略，推动更优化的临床治疗的发展。
